Atopic dermatitis in 15q24 microdeletion syndrome: a social media study.

Autor: Deydier N; Occupational and Environmental Disease Department, University Hospital 5, Avenue Foch 29609 BREST CEDEX, France, Dermatology Department, University Hospital, 5, Avenue Foch 29609 BREST CEDEX, France., Salvado M; Dermatology Department, University Hospital, 5, Avenue Foch 29609 BREST CEDEX, France., Planes M; Department of Medical Genetics, University Hospital 5, Avenue Foch 29609 BREST CEDEX, France., Misery L; Dermatology Department, University Hospital, 5, Avenue Foch 29609 BREST CEDEX, France., Abasq-Thomas C; Dermatology Department, University Hospital, 5, Avenue Foch 29609 BREST CEDEX, France.
Jazyk: angličtina
Zdroj: European journal of dermatology : EJD [Eur J Dermatol] 2023 Apr 01; Vol. 33 (2), pp. 157-159.
DOI: 10.1684/ejd.2023.4455
Abstrakt: Background: Chromosome 15q24 microdeletion is a rare genetic disorder, and the skin manifestations are poorly documented.
Objectives: In this cross-sectional observational study using social media (Facebook), we investigated the prevalence of atopic dermatitis in 15q24 microdeletion syndrome.
Materials & Methods: Parents and caregivers of a child with the syndrome were asked to participate using a validated self-reporting questionnaire.
Results: In total, 60 participants completed the questionnaire. The prevalence of atopic dermatitis was 35% among patients with chromosome 15q24 deletion. Few patients received treatment according to international guidelines.
Conclusion: We describe the largest cohort of patients with 15q24 microdeletion syndrome, revealing a high prevalence of atopic dermatitis. Patients with 15q24 microdeletion syndrome should undergo dermatological evaluation for screening and management of atopic dermatitis. Approaching individuals via social media is a successful strategy, resulting in good information which may be used to counsel families.
Databáze: MEDLINE
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