Porous SiO 2 -Based Reactor with Self-Supply of O 2 and H 2 O 2 for Synergistic Photo-Thermal/Photodynamic Therapy.
Autor: | Li Z; Department of Emergency, The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, 530007, China., Guo L; Department of Emergency, The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, 530007, China., Lin L; Department of Emergency, The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, 530007, China., Wang T; Department of Emergency, The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, 530007, China., Jiang Y; Department of Emergency, The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, 530007, China., Song J; Department of Emergency, The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, 530007, China., Feng J; Department of Emergency, The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, 530007, China., Huang J; Department of Nephrology, The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, 530007, China., Li H; Department of Nephrology, The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, 530007, China., Bai Z; College of Chemistry and Chemical Engineering, Guangxi University, Nanning, Guangxi, 530004, China., Liu W; Department of Radiation Oncology, The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, 530007, China., Zhang J; Department of Emergency, The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, 530007, China. |
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Jazyk: | angličtina |
Zdroj: | International journal of nanomedicine [Int J Nanomedicine] 2023 Jul 03; Vol. 18, pp. 3623-3639. Date of Electronic Publication: 2023 Jul 03 (Print Publication: 2023). |
DOI: | 10.2147/IJN.S387505 |
Abstrakt: | Purpose: Although the combined photo-thermal (PTT) and photodynamic therapy (PDT) of tumors have demonstrated promise as effective cancer therapy, the hypoxic and insufficient H Methods: In this work, Ce6 and hemin were loaded on graphene (GO) through π-π conjugation, and Fc was connected to GO via amide bond. The HGNs-Fc@Ce6 was loaded into SiO Results: AMS was targeted to the tumor cell and released doxorubicin. It decomposed glucose to produce H Conclusion: The results revealed that AMS had an excellent enhanced therapy effect by combining synergistic PTT and PDT. Competing Interests: The authors declare no competing interests in this work. (© 2023 Li et al.) |
Databáze: | MEDLINE |
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