Coronary allograft vasculopathy in post-heart transplant patients: pathogenesis and role of cardiac computed tomography in diagnosis-a comprehensive review.

Autor: Sharma V; Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi., Agarwal S; University of Oklahoma, Oklahoma City, OK., Grover T; Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi., Malhotra A; University of Kansas Medical Centre, Kansas City, KS., Kumar H; Dow University of Health Sciences, Karachi, Pakistan., Gowda DM; Kempegowda Institute of Medical Sciences, Bangalore., Agarwal Y; College of Medicine and Sagore Dutta Hospital, Kolkata, West Bengal., Bhatia H; Pt. B.D.S. Post Graduate Institute of Medical Sciences Rohtak, India., Koirala SB; Nepalese Army Institute of Health Sciences, Kathmandu, Nepal., Singh SP; Department of Radiology, The University of Alabama at Birmingham, AL.
Jazyk: angličtina
Zdroj: Annals of medicine and surgery (2012) [Ann Med Surg (Lond)] 2023 Jun 07; Vol. 85 (7), pp. 3531-3537. Date of Electronic Publication: 2023 Jun 07 (Print Publication: 2023).
DOI: 10.1097/MS9.0000000000000942
Abstrakt: Coronary allograft vasculopathy, often known as cardiac allograft vasculopathy (CAV), is a substantial source of morbidity and mortality in people who have had heart transplants. Early detection and monitoring of CAV are crucial for improving outcomes in this population. Although cardiac computed tomography (CT) has emerged as a possible method for finding and evaluating CAV, invasive coronary angiography has long been thought of as the gold standard for recognizing CAV. This study focuses on the utility of cardiac CT for CAV diagnosis and treatment in the post-heart transplant population. It provides an overview of recent studies on the application of cardiac CT in CAV and highlights the advantages and disadvantages of this imaging modality. The potential application of cardiac CT for CAV risk assessment and care is also examined in the study. Overall, the data point to a potential role for cardiac CT in the detection and treatment of CAV in post-heart transplant patients. It enables evaluation of the whole coronary tree and low-radiation, high-resolution imaging of the coronary arteries. Hence, further study is required to determine how best to employ cardiac CT in treating CAV in this group.
Competing Interests: The authors declare that there is no conflict of interest.
(Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc.)
Databáze: MEDLINE