Effect of addition of titanium dioxide nanoparticles on the antimicrobial properties, surface roughness and surface hardness of polymethyl methacrylate: A Systematic Review.

Autor: Kaurani P; Department of Prosthodontics, Mahatma Gandhi Dental College and Hospital, Jaipur, Rajasthan, 302022, India., Hindocha AD; Department of Prosthodontics, Sinhgad Dental College and Hospital, Pune, Maharashtra, 411041, India., Jayasinghe RM; Department of Prosthetic Dentistry, Faculty of Dental Sciences , University of Peradeniya, Kandy, Central province, 20400, Sri Lanka., Pai UY; Department of Prosthodontics, Manipal College of Dental Sciences, Mangalore, Karnataka, 575004, India., Batra K; Department of Medical Education, Kirk Kerkorian School of Medicine at University of Nevada, Las Vegas, Nevada, 89102, USA., Price C; Health Professions Librarian, Albert S. Cook Library, Towson University, Towson, Maryland, 21252, USA.
Jazyk: angličtina
Zdroj: F1000Research [F1000Res] 2023 May 31; Vol. 12, pp. 577. Date of Electronic Publication: 2023 May 31 (Print Publication: 2023).
DOI: 10.12688/f1000research.130028.1
Abstrakt: Background: Polymethyl Methacrylate (PMMA) denture-base resins have poor surface properties that facilitates microbial adhesion causing denture stomatitis. This systematic review aims to evaluate the effect of different sizes and percentages of titanium dioxide nanoparticles (TiO2NP) on the antimicrobial property, surface roughness and surface hardness of PMMA denture base resin.  Methods: A systematic search of English peer-reviewed articles, clinical trial registries, grey literature databases and other online sources was performed using the PRISMA-S Guidelines for In-Vivo and In-Vitro studies. Qualitative data synthesis was performed to analyse sample dimensions, acrylic used, treatments of nanoparticles, methods used for testing and effect of size and percentage of nanoparticle. Risk of bias assessment was done using modified Cochrane risk of bias tool. Results: Out of 1376 articles, 15 were included. TiO 2 NP of size less than 30 nm was most frequently used. Both antimicrobial property and surface hardness improved irrespective of the size of the added TiO 2 NP. Three studies reported increase in the surface roughness with less than 50 nm TiO 2 NP.  3% TiO 2 NP was most frequently used. On increasing the percentage, three studies reported an increase in antimicrobial property, while two studies found no change. With TiO 2 NP greater than or equal to 3%, six studies reported an increase in surface hardness, while two reported increase in surface roughness. Large methodological variations were observed across studies. All studies except one were of moderate quality. Conclusions:   On addition of TiO 2 NP to heat polymerized PMMA, the antimicrobial property and surface hardness improved irrespective of the size of the TiO 2 NP, however, addition of nanoparticles less than 50 nm increased the surface roughness. Increasing the percentage of TiO 2 NP increased the surface hardness but did not always increase the antimicrobial property. Addition of 3% TiO 2 NP provided optimum results with regards to antimicrobial effect and surface hardness, but increase in the surface roughness.
Competing Interests: No competing interests were disclosed.
(Copyright: © 2023 Kaurani P et al.)
Databáze: MEDLINE
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