Evaluation of serum iron status indicators in patients with primary open angle glaucoma.
| Autor: | Seyyar SA; Ophthalmology Department, Gaziantep University Hospital, Gaziantep, Turkey., Tokuc EO; Ophthalmology Department, Kocaeli University Hospital, Kocaeli, Turkey., Güngör K; Ophthalmology Department, Gaziantep University Hospital, Gaziantep, Turkey. |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | European journal of ophthalmology [Eur J Ophthalmol] 2024 Jan; Vol. 34 (1), pp. 175-180. Date of Electronic Publication: 2023 Jul 09. |
| DOI: | 10.1177/11206721231187427 |
| Abstrakt: | Purpose: To investigate the relationship between serum iron status indicators (ferritin) levels and POAG. Methods: The files of all glaucoma patients who applied to the ophthalmology clinic between January 2018 and January 2022 were reviewed retrospectively. Laboratory data from fasting blood tests, internal medicine outpatient clinic reports, and extensive ophthalmologic examination data, including fundus photographs showing the optic disc, were collected from the files. A control group was formed from individuals with adequate general and eye health, age- and gender-matched individuals who had undergone examination in the ophthalmology clinic within the same date range. Serum iron status indicators and some laboratory data of POAG patients and healthy controls were compared. Result: Of our participants, consisting of 65 patients with POAG and 72 healthy controls, 84 (61.32%) were female and 53 (38.68%) were male. It was observed that serum ferritin level was significantly higher in POAG patients compared to healthy controls, and the total iron binding capacity was significantly lower (respectively (p = 0.022), (p = 0.002). In logistic regression analysis, it was found that the risk of POAG increased in cases with high serum ferritin levels (OR = 0.982; p = 0.012). In addition, the risk of POAG was found to increase in cases where MCV was lower (OR = 1.121; p = 0.039). Conclusion: This study shows that higher serum ferritin levels are associated with a higher risk of POAG. Competing Interests: Declaration of conflicting interestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. |
| Databáze: | MEDLINE |
| Externí odkaz: |
|