Long-term air pollution exposure and malignant intracranial tumours of the central nervous system: a pooled analysis of six European cohorts.
Autor: | Hvidtfeldt UA; Danish Cancer Society Research Center, Copenhagen, Denmark. ullah@cancer.dk., Chen J; Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands., Rodopoulou S; Department of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, Athens, Greece., Strak M; Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands.; National Institute for Public Health and the Environment, Bilthoven, The Netherlands., de Hoogh K; Swiss Tropical and Public Health Institute, Basel, Switzerland.; University of Basel, Basel, Switzerland., Andersen ZJ; Department of Public Health, University of Copenhagen, Copenhagen, Denmark., Bellander T; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.; Centre for Occupational and Environmental Medicine, Region Stockholm, Stockholm, Sweden., Brandt J; Department of Environmental Science, Aarhus University, Roskilde, Denmark.; iClimate-interdisciplinary Centre for Climate Change, Aarhus University, Roskilde, Denmark., Fecht D; MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK., Forastiere F; Department of Epidemiology, Lazio Region Health Service/ASL Roma 1, Rome, Italy.; Environmental Research Group, School of Public Health, Faculty of Medicine, Imperial College, London, London, UK., Gulliver J; MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; Centre for Environmental Health and Sustainability & School of Geography, Geology and the Environment, University of Leicester, Leicester, UK., Hertel O; Departments of Ecoscience, Aarhus University, Roskilde, Denmark., Hoffmann B; Institute for Occupational, Social and Environmental Medicine, Centre for Health and Society, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Katsouyanni K; Department of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, Athens, Greece.; MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK., Ketzel M; Department of Environmental Science, Aarhus University, Roskilde, Denmark.; Global Centre for Clean Air Research (GCARE), University of Surrey, Guildford, GU2 7XH, UK., Leander K; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Magnusson PKE; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Nagel G; Institute of Epidemiology and Medical Biometry, Ulm University, Ulm, Germany., Pershagen G; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.; Centre for Occupational and Environmental Medicine, Region Stockholm, Stockholm, Sweden., Rizzuto D; Department of Neurobiology, Care Sciences, and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.; Stockholm Gerontology Research Center, Stockholm, Sweden., Samoli E; Department of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, Athens, Greece., So R; Department of Public Health, University of Copenhagen, Copenhagen, Denmark., Stafoggia M; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.; Department of Epidemiology, Lazio Region Health Service/ASL Roma 1, Rome, Italy., Tjønneland A; Danish Cancer Society Research Center, Copenhagen, Denmark.; Department of Public Health, University of Copenhagen, Copenhagen, Denmark., Weinmayr G; Institute of Epidemiology and Medical Biometry, Ulm University, Ulm, Germany., Wolf K; Institute of Epidemiology, Helmholtz Zentrum München, Neuherberg, Germany., Zhang J; Department of Public Health, University of Copenhagen, Copenhagen, Denmark., Zitt E; Agency for Preventive and Social Medicine (aks), Bregenz, Austria.; Department of Internal Medicine 3, LKH Feldkirch, Feldkirch, Austria., Brunekreef B; Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands., Hoek G; Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands., Raaschou-Nielsen O; Danish Cancer Society Research Center, Copenhagen, Denmark.; Department of Environmental Science, Aarhus University, Roskilde, Denmark. |
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Jazyk: | angličtina |
Zdroj: | British journal of cancer [Br J Cancer] 2023 Sep; Vol. 129 (4), pp. 656-664. Date of Electronic Publication: 2023 Jul 07. |
DOI: | 10.1038/s41416-023-02348-1 |
Abstrakt: | Background: Risk factors for malignant tumours of the central nervous system (CNS) are largely unknown. Methods: We pooled six European cohorts (N = 302,493) and assessed the association between residential exposure to nitrogen dioxide (NO Results: During 5,497,514 person-years of follow-up (average 18.2 years), we observed 623 malignant CNS tumours. The results of the fully adjusted linear analyses showed a hazard ratio (95% confidence interval) of 1.07 (0.95, 1.21) per 10 μg/m³ NO Conclusions: We observed indications of an association between exposure to NO (© 2023. The Author(s), under exclusive licence to Springer Nature Limited.) |
Databáze: | MEDLINE |
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