A meta-analysis comparing phenol treatment with surgical excision for pilonidal sinus.

Autor:	Gan XX; Shijiazhuang People's Hospital, China., Liu P; Shijiazhuang People's Hospital, China., Chen SH; Shijiazhuang People's Hospital, China., Li J; Shijiazhuang People's Hospital, China., Zhao X; Shijiazhuang People's Hospital, China., Chen W; Shijiazhuang People's Hospital, China., Zhang J; Shijiazhuang People's Hospital, China., Yang CP; Shijiazhuang People's Hospital, China., Wang MX; Shijiazhuang People's Hospital, China., Wang LW; Shijiazhuang People's Hospital, China., Zhang D; Shijiazhuang People's Hospital, China., Xu X; Shijiazhuang People's Hospital, China., Dai GY; Department of Anus and Intestine Surgery, Shijiazhuang People's Hospital Affiliated to Hebei Medical University, China. Electronic address: dgy698@163.com.
Jazyk:	angličtina
Zdroj:	Asian journal of surgery [Asian J Surg] 2024 Jan; Vol. 47 (1), pp. 8-15. Date of Electronic Publication: 2023 Jul 05.
DOI:	10.1016/j.asjsur.2023.06.111
Abstrakt:	Pilonidal sinus is a chronic condition characterized by inflammation, swelling, and pain in the sacrococcygeal region. In recent years, the rate of recurrence and wound complications in PSD remains high, and no treatment is universally accepted. This study aimed to compare the efficacy of phenol treatment with surgical excision treatment for PSD through a meta-analysis of controlled clinical trials. We searched three electronic databases, PubMed, Embase, and Cochrane library, to comprehensively search the literature comparing phenol treatment and surgical treatment of pilonidal sinus. Fourteen publications were included, including five RCTs and nine non-RCTs. The phenol group had a slightly higher rate of disease recurrence than the surgical group (RR = 1.12, 95% CI [0.77,1.63]), but the difference was not statistically significant (P = 0.55 > 0.05). As compared to the surgical group, wound complications were considerably less common (RR = 0.40, 95% CI [0.27,0.59]). Phenol treatment resulted in a significantly shorter operating time than surgery treatment (weighted mean difference -22.76, 95% CI [-31.13,-14.39]). The time to return to daily work was considerably shorter than in the surgical group (weighted mean difference -10.11, 95% CI [-14.58,-5.65]). Postoperative complete healing time was significantly shorter than surgical healing time (weighted mean difference -17.11, 95% CI [-32.18,-2.03]). Phenol treatment is effective for pilonidal sinus disease, and its recurrence rate is not significantly different from surgical treatment. The greatest advantage of phenol treatment is the low incidence of wound complications. Moreover, the time required for treatment and recovery are significantly lower than for surgical treatment. Competing Interests: Declarations of competing interest none. (Copyright © 2023 Asian Surgical Association and Taiwan Robotic Surgery Association. Published by Elsevier B.V. All rights reserved.)
Databáze:	MEDLINE
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