Dietary pattern in autism increases the need for probiotic supplementation: A comprehensive narrative and systematic review on oxidative stress hypothesis.

Autor: Zarezadeh M; Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran., Mahmoudinezhad M; Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran., Hosseini B; Clinical Research and Knowledge Transfer Unit on Childhood Asthma, Research Centre, Sainte-Justine University Health Centre, Montreal, QC H3T 1C5, Canada., Khorraminezhad L; School of Human Nutrition, McGill University, Ste-Anne-de-Bellevue, Québec, Canada., Razaghi M; Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Alvandi E; School of Medicine, Western Sydney University, NSW, Australia., Saedisomeolia A; School of Human Nutrition, McGill University, Ste-Anne-de-Bellevue, Québec, Canada. Electronic address: ahmad.saedisomeolia@mcgill.ca.
Jazyk: angličtina
Zdroj: Clinical nutrition (Edinburgh, Scotland) [Clin Nutr] 2023 Aug; Vol. 42 (8), pp. 1330-1358. Date of Electronic Publication: 2023 Jun 15.
DOI: 10.1016/j.clnu.2023.06.014
Abstrakt: Autism spectrum disorders (ASDs) are associated with specific dietary habits, including limited food selection and gastrointestinal problems, resulting in an altered gut microbiota. Autistic patients have an elevated abundance of certain gut bacteria associated with increased oxidative stress in the gastrointestinal tract. Probiotic supplementation has been shown to decrease oxidative stress in a simulated gut model, but the antioxidant effects of probiotics on the oxidative stress of the gut in autistic patients have not been directly studied. However, it is speculated that probiotic supplementation may help decrease oxidative stress in the gastrointestinal tract of autistic patients due to their specific dietary habits altering the microbiota. PubMed, Scopus and Web of Science databases and Google Scholar were searched up to May 2023. This systematic-narrative review aims to present the latest evidence regarding the changes in eating habits of autistic children which may further increase the gut microbiota induced oxidative stress. Additionally, this review will assess the available literature on the effects of probiotic supplementation on oxidative stress parameters.
Competing Interests: Conflict of interest Authors declare no conflict of interest.
(Copyright © 2023 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.)
Databáze: MEDLINE
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