Comparison of behavioral activation-enhanced cognitive processing therapy and cognitive processing therapy among U.S. service members: A randomized clinical trial.

Autor: Walter KH; Health and Behavioral Sciences, Naval Health Research Center, San Diego, CA, USA. Electronic address: kristen.h.walter.civ@health.mil., Hunt WM; Directorate of Mental Health, Naval Medical Center San Diego, San Diego, CA, USA., Otis NP; Health and Behavioral Sciences, Naval Health Research Center, San Diego, CA, USA; Leidos, Inc., San Diego, CA, USA., Kline AC; Health and Behavioral Sciences, Naval Health Research Center, San Diego, CA, USA; Leidos, Inc., San Diego, CA, USA., Miggantz EL; Health and Behavioral Sciences, Naval Health Research Center, San Diego, CA, USA; Leidos, Inc., San Diego, CA, USA., Thomsen CJ; Health and Behavioral Sciences, Naval Health Research Center, San Diego, CA, USA., Glassman LH; Health and Behavioral Sciences, Naval Health Research Center, San Diego, CA, USA; Leidos, Inc., San Diego, CA, USA.
Jazyk: angličtina
Zdroj: Psychiatry research [Psychiatry Res] 2023 Aug; Vol. 326, pp. 115330. Date of Electronic Publication: 2023 Jul 04.
DOI: 10.1016/j.psychres.2023.115330
Abstrakt: Posttraumatic stress disorder (PTSD) and major depressive disorder (MDD) frequently co-occur and can cause significant impairment. Data are lacking as to whether interventions targeting both PTSD and MDD may improve treatment outcomes among individuals with this comorbidity compared with existing evidence-based PTSD treatments alone. This randomized trial compared the effectiveness of cognitive processing therapy (CPT) enhanced with behavioral activation (BA+CPT) versus CPT among 94 service members (52 women and 42 men; age M = 28.5 years) with comorbid PTSD and MDD. The primary outcome was clinician-administered depression symptom severity on the Montgomery-Åsberg Depression Rating Scale (MADRS) from pretreatment through 3-month follow-up. Intent-to-treat analyses using multilevel models showed statistically and clinically significant decreases in MADRS scores for both conditions over time, with no significant differences between BA+CPT and CPT. Secondary depression and PTSD symptom outcomes followed a similar pattern of results. For diagnostic MDD and PTSD outcomes using available data, no statistically significant differences between treatments emerged at posttreatment or 3-month follow-up. Sessions attended, dropout rate, and treatment satisfaction did not significantly differ between treatments. Outcomes were comparable for both treatments, suggesting that BA+CPT and CPT were similarly effective psychotherapy options for comorbid PTSD and MDD.
Competing Interests: Declaration of Competing Interest None of the authors have any conflicts of interest or competing interests to report.
(Copyright © 2023. Published by Elsevier B.V.)
Databáze: MEDLINE
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