| Autor: |
Silva AAD; Federal University of Ceará, Fortaleza, Brazil. vanescafm@hotmail.com., Pérez EMDS; University Center Estacio de Sá, Via Corpvs, Fortaleza, Brazil., Figueiredo IST; Federal University of Ceará, Fortaleza, Brazil. vanescafm@hotmail.com., Alencar NMN; Federal University of Ceará, Fortaleza, Brazil. vanescafm@hotmail.com., Alves APNN; Federal University of Ceará, Fortaleza, Brazil. vanescafm@hotmail.com., Fernandes FAN; Federal University of Ceará, Fortaleza, Brazil. vanescafm@hotmail.com., Vasconcelos RP; Ceará State University, Fortaleza, Brazil., Oliveira AC; Ceará State University, Fortaleza, Brazil., Gaban SVF; Federal University of Ceará, Fortaleza, Brazil. vanescafm@hotmail.com. |
| Jazyk: |
angličtina |
| Zdroj: |
Food & function [Food Funct] 2023 Jul 31; Vol. 14 (15), pp. 6853-6863. Date of Electronic Publication: 2023 Jul 31. |
| DOI: |
10.1039/d3fo01447a |
| Abstrakt: |
This study investigated the effects of virgin coconut oil (VCO) on body weight, white fat depots, and biochemical and morphological parameters in male Swiss mice fed standard (SD) or high-fat (HFD) diets. Thirty-three adult animals were assigned to one of four groups, as follows: SD, SD plus VCO (SDCO), HFD, and HFD plus VCO (HFDCO). VCO had no effects on the Lee index, subcutaneous fat, periepididymal fat, retroperitoneal fat, area under the curve for glucose, or pancreas weight, all of which were increased by HFD. Low-density lipoprotein cholesterol increased in the SDCO group compared with the SD group and decreased in the HFDCO group compared with the HFD group. VCO increased total cholesterol only in the SDCO group compared with the SD group, with no differences between the HFD and HFDCO groups. In conclusion, low-dose VCO supplementation did not improve obesity, had no effects on hepatic or renal function, and had beneficial effects on the lipid profile only in animals fed HFD. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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