Evaluation of novel beverage formulations for hydration enhancement in humans.

Autor: Tinsley GM; Energy Balance & Body Composition Laboratory; Department of Kinesiology & Sport Management, Texas Tech University, Lubbock, TX, USA., Siedler MR; Energy Balance & Body Composition Laboratory; Department of Kinesiology & Sport Management, Texas Tech University, Lubbock, TX, USA., Rodriguez C; Energy Balance & Body Composition Laboratory; Department of Kinesiology & Sport Management, Texas Tech University, Lubbock, TX, USA., Harty PS; Energy Balance & Body Composition Laboratory; Department of Kinesiology & Sport Management, Texas Tech University, Lubbock, TX, USA.; Department of Kinesiology; College of Science, Technology, and Health; Lindenwood University, St. Charles, MO, USA., Stratton MT; Energy Balance & Body Composition Laboratory; Department of Kinesiology & Sport Management, Texas Tech University, Lubbock, TX, USA.; Department of Health, Kinesiology and Sport; University of South Alabama, Mobile, AL, USA., White SJ; Energy Balance & Body Composition Laboratory; Department of Kinesiology & Sport Management, Texas Tech University, Lubbock, TX, USA., Keith DS; Energy Balance & Body Composition Laboratory; Department of Kinesiology & Sport Management, Texas Tech University, Lubbock, TX, USA., Green JJ; Energy Balance & Body Composition Laboratory; Department of Kinesiology & Sport Management, Texas Tech University, Lubbock, TX, USA., Boykin JR; Energy Balance & Body Composition Laboratory; Department of Kinesiology & Sport Management, Texas Tech University, Lubbock, TX, USA., Williams AD; Energy Balance & Body Composition Laboratory; Department of Kinesiology & Sport Management, Texas Tech University, Lubbock, TX, USA., DeHaven B; Energy Balance & Body Composition Laboratory; Department of Kinesiology & Sport Management, Texas Tech University, Lubbock, TX, USA., Brojanac A; Energy Balance & Body Composition Laboratory; Department of Kinesiology & Sport Management, Texas Tech University, Lubbock, TX, USA., Tinoco E; Energy Balance & Body Composition Laboratory; Department of Kinesiology & Sport Management, Texas Tech University, Lubbock, TX, USA.
Jazyk: angličtina
Zdroj: Journal of electrical bioimpedance [J Electr Bioimpedance] 2023 Apr 26; Vol. 14 (1), pp. 3-12. Date of Electronic Publication: 2023 Apr 26 (Print Publication: 2023).
DOI: 10.2478/joeb-2023-0002
Abstrakt: This study evaluated the influence of novel beverage formulations on bioimpedance- and urine-based hydration markers. Thirty young healthy adults (n=16 females, n=14 males; age: 23.2±3.7 years; BMI: 24.3±3.3 kg/m 2 ) participated in a randomized, double-blind, placebo-controlled, crossover study. Participants completed three conditions with baseline bioimpedance, urine, and body mass assessments, followed by ingestion of one liter of a test beverage over a 30-minute period. The three beverages were: active hydration formulation in still (AFstill) or sparkling (AFspark) water and a still water control. The active formulations were identical in concentrations of alpha-cyclodextrin and complexing agents. Following beverage ingestion, bioimpedance assessments were performed every 15 minutes for two hours, followed by final urinary and body mass assessments. The primary bioimpedance outcomes were phase angle at 50 kHz, resistance of the extra-cellular compartment (R 0 ), and resistance of the intracellular compartment (Ri). Data were analyzed using linear mixed effects models, Friedman tests, and Wilcoxon tests. Statistically significant changes in phase angle values were observed at 30 (p=0.004) and 45 minutes (p=0.024) following the initiation of beverage ingestion in the AFstill condition as compared to the reference model (i.e., control condition at baseline). Although differences between conditions were not statistically significant at later time points, the data were consistent with AFstill having greater elevations in phase angle throughout the monitoring period. At the 30-minute time point only, statistically significant differences in R 0 for AFspark (p<0.001) and in Ri for AFstill (p=0.008) were observed. When averaged across post-ingestion time points, there was a trend (p=0.08) for Ri differences between conditions. The net fluid balance was greater than zero, indicating retention of ingested fluid, for AFstill (p=0.02) and control (p=0.03), with a trend for AFspark (p=0.06). In conclusion, an active formulation containing alpha-cyclodextrin in still water demonstrated potential benefits for enhancing hydration markers in humans.
Competing Interests: Conflict of interest Authors state no conflict of interest. This study was funded through research grants from 8 POiNT LLC, who is leading scientific and product validation on a patented hydration technology (Award Numbers A21-0085-001, A21-0085-002, and A21-0284-001). 8 POiNT LLC provided general input on the outcomes of interest but did not play a direct role in the details of study design, nor any role in data collection or analysis. Per the research contract, the sponsor was allowed to review the manuscript for technical considerations but did not play other roles in the writing of the manuscript.
(© 2023 Grant M. Tinsley et al., published by Sciendo.)
Databáze: MEDLINE
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