Postoperative Ovarian Vein Thrombosis and Treatment with Direct Oral Anticoagulant.

Autor: Shukr G; Department of Minimally Invasive Gynecologic Surgery, Henry Ford Hospital, Detroit, Michigan, USA., Gonte MR; Department of Minimally Invasive Gynecologic Surgery, Henry Ford Hospital, Detroit, Michigan, USA.; Department of Medicine, Wayne State University School of Medicine, Detroit, Michigan, USA.; Department of Global Health and Population, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA., Webber VE; Department of Minimally Invasive Gynecologic Surgery, Henry Ford Hospital, Detroit, Michigan, USA.; Department of Medicine, Wayne State University School of Medicine, Detroit, Michigan, USA., Abood JA; Department of Minimally Invasive Gynecologic Surgery, Henry Ford Hospital, Detroit, Michigan, USA., Arsanious S; Department of Minimally Invasive Gynecologic Surgery, Henry Ford Hospital, Detroit, Michigan, USA., Eisenstein D; Department of Minimally Invasive Gynecologic Surgery, Henry Ford Hospital, Detroit, Michigan, USA.
Jazyk: angličtina
Zdroj: Gynecology and minimally invasive therapy [Gynecol Minim Invasive Ther] 2023 Apr 19; Vol. 12 (2), pp. 113-115. Date of Electronic Publication: 2023 Apr 19 (Print Publication: 2023).
DOI: 10.4103/gmit.gmit_62_22
Abstrakt: Postoperative ovarian vein thrombosis (OVT) is a rare complication following hysterectomy. Due to its ambiguous presentation, most frequently presenting as a fever with no known source and lower quadrant abdominal pain, OVTs are commonly diagnosed incidentally on computed tomography as a low-attenuation thrombus in place of the ovarian vein. The cornerstones of OVT treatment include anticoagulation and antibiotic therapy; however, there are no current guidelines to inform provider decision-making regarding specific anticoagulant agents, dosing, or length of therapy. We present a patient with a history of deep-vein thrombosis, who presented to the emergency department with OVT following a laparoscopic hysterectomy. She was treated with apixaban, a direct oral anticoagulant (DOAC), and experienced repeated episodes of vaginal bleeding and hematoma expansion. We present this case to instill a high index of suspicion for OVT after laparoscopic hysterectomy, and to discuss the role of DOACs in patients with thromboembolic disease and concurrent bleeding.
Competing Interests: There are no conflicts of interest.
(Copyright: © 2023 Gynecology and Minimally Invasive Therapy.)
Databáze: MEDLINE