Resistance training prescription for muscle strength and hypertrophy in healthy adults: a systematic review and Bayesian network meta-analysis.

Autor:	Currier BS; Department of Kinesiology, Faculty of Science, McMaster University, Hamilton, Ontario, Canada., Mcleod JC; Department of Kinesiology, Faculty of Science, McMaster University, Hamilton, Ontario, Canada., Banfield L; Health Sciences Library, McMaster University, Hamilton, Ontario, Canada., Beyene J; Department of Health Research Methods, Evidence, and Impact, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada., Welton NJ; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., D'Souza AC; Department of Kinesiology, Faculty of Science, McMaster University, Hamilton, Ontario, Canada., Keogh JAJ; Department of Kinesiology, Faculty of Science, McMaster University, Hamilton, Ontario, Canada., Lin L; Department of Kinesiology, Faculty of Science, McMaster University, Hamilton, Ontario, Canada., Coletta G; Department of Kinesiology, Faculty of Science, McMaster University, Hamilton, Ontario, Canada., Yang A; Department of Kinesiology, Faculty of Science, McMaster University, Hamilton, Ontario, Canada., Colenso-Semple L; Department of Kinesiology, Faculty of Science, McMaster University, Hamilton, Ontario, Canada., Lau KJ; Department of Kinesiology, Faculty of Science, McMaster University, Hamilton, Ontario, Canada., Verboom A; Department of Kinesiology, Faculty of Science, McMaster University, Hamilton, Ontario, Canada., Phillips SM; Department of Kinesiology, Faculty of Science, McMaster University, Hamilton, Ontario, Canada phillis@mcmaster.ca.
Jazyk:	angličtina
Zdroj:	British journal of sports medicine [Br J Sports Med] 2023 Sep; Vol. 57 (18), pp. 1211-1220. Date of Electronic Publication: 2023 Jul 06.
DOI:	10.1136/bjsports-2023-106807
Abstrakt:	Objective: To determine how distinct combinations of resistance training prescription (RTx) variables (load, sets and frequency) affect muscle strength and hypertrophy. Data Sources: MEDLINE, Embase, Emcare, SPORTDiscus, CINAHL, and Web of Science were searched until February 2022. Eligibility Criteria: Randomised trials that included healthy adults, compared at least 2 predefined conditions (non-exercise control (CTRL) and 12 RTx, differentiated by load, sets and/or weekly frequency), and reported muscle strength and/or hypertrophy were included. Analyses: Systematic review and Bayesian network meta-analysis methodology was used to compare RTxs and CTRL. Surface under the cumulative ranking curve values were used to rank conditions. Confidence was assessed with threshold analysis. Results: The strength network included 178 studies (n=5097; women=45%). The hypertrophy network included 119 studies (n=3364; women=47%). All RTxs were superior to CTRL for muscle strength and hypertrophy. Higher-load (>80% of single repetition maximum) prescriptions maximised strength gains, and all prescriptions comparably promoted muscle hypertrophy. While the calculated effects of many prescriptions were similar, higher-load, multiset, thrice-weekly training (standardised mean difference (95% credible interval); 1.60 (1.38 to 1.82) vs CTRL) was the highest-ranked RTx for strength, and higher-load, multiset, twice-weekly training (0.66 (0.47 to 0.85) vs CTRL) was the highest-ranked RTx for hypertrophy. Threshold analysis demonstrated these results were extremely robust. Conclusion: All RTx promoted strength and hypertrophy compared with no exercise. The highest-ranked prescriptions for strength involved higher loads, whereas the highest-ranked prescriptions for hypertrophy included multiple sets. Prospero Registration Number: CRD42021259663 and CRD42021258902. Competing Interests: Competing interests: SMP reports grants or research contracts from the US National Dairy Council, Canadian Institutes for Health Research, Dairy Farmers of Canada, Roquette Freres, Ontario Centre of Innovation, Nestle Health Sciences, Myos, National Science and Engineering Research Council and the US NIH during the conduct of the study; personal fees from Nestle Health Sciences, non-financial support from Enhanced Recovery, outside the submitted work. SMP has patents licensed to Exerkine but reports no financial gains from any patent or related work. The remaining authors report no competing interests. (© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
Databáze:	MEDLINE
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