Recovery From Acute Respiratory Distress Syndrome Is Associated With Increasing Alpha Power in the Frontal Electroencephalogram During Propofol Sedation: A Case Report.

Autor: Guay CS; From the Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.; Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, Massachusetts., Bean CD; From the Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts., Kwon O; From the Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.; Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, Massachusetts.; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Brown EN; From the Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.; Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, Massachusetts.; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, Massachusetts.
Jazyk: angličtina
Zdroj: A&A practice [A A Pract] 2023 Jul 05; Vol. 17 (7), pp. e01698. Date of Electronic Publication: 2023 Jul 05 (Print Publication: 2023).
DOI: 10.1213/XAA.0000000000001698
Abstrakt: The effects of critical illness on electroencephalographic (EEG) signatures of sedatives have not been described, limiting the use of EEG-guided sedation in the intensive care unit (ICU). We report the case of a 36-year-old man recovering from acute respiratory distress syndrome (ARDS). Severe ARDS was characterized by slow-delta (0.1-4 Hz) and theta (4-8 Hz) oscillations but lacked the alpha (8-14 Hz) power expected during propofol sedation in a patient of this age. The alpha power emerged as ARDS resolved. This case raises the question of whether inflammatory states can alter EEG signatures during sedation.
Competing Interests: Conflicts of Interest: See Disclosures at the end of the article.
(Copyright © 2023 International Anesthesia Research Society.)
Databáze: MEDLINE