Contemporary Polygenic Scores of Low-Density Lipoprotein Cholesterol and Coronary Artery Disease Predict Coronary Atherosclerosis in Adolescents and Young Adults.

Autor: Guarischi-Sousa R; Department of Medicine, Division of Cardiovascular Medicine (R.G.-S., P.F.K., K.R.I., P.S.T., S.L.C., T.L.A.)., Salfati E; Scripps Research Translational Institute at Scripps Research, La Jolla, CA (E.S.)., Kho PF; Department of Medicine, Division of Cardiovascular Medicine (R.G.-S., P.F.K., K.R.I., P.S.T., S.L.C., T.L.A.)., Iyer KR; Department of Medicine, Division of Cardiovascular Medicine (R.G.-S., P.F.K., K.R.I., P.S.T., S.L.C., T.L.A.)., Hilliard AT; VA Palo Alto Health Care System, CA (A.T.H., P.S.T., S.L.C., T.L.A.)., Herrington DM; Department of Internal Medicine, Section on Cardiovascular Medicine, Wake Forest School of Medicine, Winston-Salem, NC (D.M.H.)., Tsao PS; Department of Medicine, Division of Cardiovascular Medicine (R.G.-S., P.F.K., K.R.I., P.S.T., S.L.C., T.L.A.).; Cardiovascular Institute (P.S.T., T.L.A.).; VA Palo Alto Health Care System, CA (A.T.H., P.S.T., S.L.C., T.L.A.)., Clarke SL; Department of Medicine, Division of Cardiovascular Medicine (R.G.-S., P.F.K., K.R.I., P.S.T., S.L.C., T.L.A.).; Department of Pediatrics, Division of Pediatric Cardiology, Stanford University School of Medicine, CA (S.L.C.).; VA Palo Alto Health Care System, CA (A.T.H., P.S.T., S.L.C., T.L.A.)., Assimes TL; Department of Medicine, Division of Cardiovascular Medicine (R.G.-S., P.F.K., K.R.I., P.S.T., S.L.C., T.L.A.).; Department of Epidemiology and Population Health (T.L.A.).; Cardiovascular Institute (P.S.T., T.L.A.).; VA Palo Alto Health Care System, CA (A.T.H., P.S.T., S.L.C., T.L.A.).
Jazyk: angličtina
Zdroj: Circulation. Genomic and precision medicine [Circ Genom Precis Med] 2023 Oct; Vol. 16 (5), pp. 480-482. Date of Electronic Publication: 2023 Jul 06.
DOI: 10.1161/CIRCGEN.122.004047
Abstrakt: Competing Interests: Disclosures None.
Databáze: MEDLINE