Accessing the biotechnological potential of a novel isolated microalga from a semi-arid region of Brazil.

Autor:	Lima ASP; Departamento de Bioquímica, Universidade Federal de Pernambuco, Cidade Universitária, Recife, PE, Brazil., Cahú TB; Departamento de Bioquímica, Universidade Federal de Pernambuco, Cidade Universitária, Recife, PE, Brazil., Dantas DMM; Departamento de Pesca e Aquicultura, Universidade Federal Rural de Pernambuco, Recife, PE, Brazil., Veras BO; Departamento de Bioquímica, Universidade Federal de Pernambuco, Cidade Universitária, Recife, PE, Brazil., Oliveira CYB; Departamento de Pesca e Aquicultura, Universidade Federal Rural de Pernambuco, Recife, PE, Brazil., Souza RS; Departamento de Pesca e Aquicultura, Universidade Federal Rural de Pernambuco, Recife, PE, Brazil., Moraes LBS; Departamento de Pesca e Aquicultura, Universidade Federal Rural de Pernambuco, Recife, PE, Brazil., Silva FCO; Departamento de Bioquímica, Universidade Federal de Pernambuco, Cidade Universitária, Recife, PE, Brazil., Araújo MIF; Departamento de Bioquímica, Universidade Federal de Pernambuco, Cidade Universitária, Recife, PE, Brazil., Gálvez AO; Departamento de Pesca e Aquicultura, Universidade Federal Rural de Pernambuco, Recife, PE, Brazil., Souza RB; Departamento de Bioquímica, Universidade Federal de Pernambuco, Cidade Universitária, Recife, PE, Brazil.
Jazyk:	angličtina
Zdroj:	Food science and technology international = Ciencia y tecnologia de los alimentos internacional [Food Sci Technol Int] 2023 Jul 05, pp. 10820132231186171. Date of Electronic Publication: 2023 Jul 05.
DOI:	10.1177/10820132231186171
Abstrakt:	The use of microalgae as a source of food and pharmaceutical ingredients has garnered growing interest in recent years. Despite the rapid growth of the nutraceutical market, knowledge about the potential of bioactive molecules from microalgae remains insufficient. The present study aimed to investigate the biotechnological potential of the green microalga Desmodesmus armatus isolated from a semi-arid region of Brazil. The algal biomass was characterized in terms of gross biochemical composition, exopolysaccharide content, enzymatic inhibition capacity, and antioxidant, antibacterial, and hemolytic activities from solvents of different polarities (water, ethanol, acetone, and hexane). D armatus biomass had 40% of crude protein content, 25.94% of lipids, and 25.03% of carbohydrates. The prebiotic potential of exopolysaccharides from D armatus was demonstrated, which stimulated the growth of Lacticaseibacillus rhamnosus and Lactiplantibacillus plantarum bacteria strains. Moreover, the enzyme inhibition capacity for the proteases chymotrypsin (34.78%-45.8%) and pepsin (16.64%-27.27%), in addition to α-amylase (24.79%) and lipase (31.05%) was confirmed. The antioxidant potential varied between the different extracts, with 2,2-diphenyl-1-picrylhydrazyl sequestration values varying between 17.51% and 63.12%, and those of the 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) method between 6.82% and 22.89%. In the antibacterial activity test, only the ethanolic extract showed inhibition against Listeria sp. (at minimum inhibitory concentration [MIC] = 256 µg mL -1 ). This fraction also presented the highest significant levels of hemolysis (31.88%-52.45%). In summary, the data presented in the study suggest the presence of biocompounds with biotechnological and nutraceutical potential in the D armatus biomass. Future studies may evaluate the inclusion of this biomass in foods in order to increase their biological value. Competing Interests: Declaration of conflicting interestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Databáze:	MEDLINE
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