Hypopituitarism After Mild Traumatic Brain Injury: A Case Report.

Autor: McLoughlin RJ; Physical Medicine and Rehabilitation, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA., Swanson RL 2nd; Center for Neurotrauma, Neurodegeneration and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, USA.; Physical Medicine and Rehabilitation, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2023 Jul 02; Vol. 15 (7), pp. e41282. Date of Electronic Publication: 2023 Jul 02 (Print Publication: 2023).
DOI: 10.7759/cureus.41282
Abstrakt: Hypopituitarism is characterized by an underactive pituitary gland and may result in growth hormone deficiency, hypothyroidism, testosterone deficiency, and/or adrenal insufficiency. Traumatic brain injury (TBI) exposure is a known risk factor for hypopituitarism. However, patients with hypopituitarism secondary to TBI exposure may go undiagnosed because the signs and symptoms of hypopituitarism can be subtle. This case report describes a 40-year-old male US military veteran who endorsed fatigue, sexual dysfunction, and weight gain several years after experiencing multiple mild TBIs during his military service. He ultimately underwent a full neuroendocrine workup that revealed low testosterone in addition to previously diagnosed hypothyroidism with a resolution of symptoms after starting testosterone therapy.
Competing Interests: RLS serves as an elected, unpaid, Consumer Advisory Board (CAB) member for the joint United States Department of Veterans Affairs and United States Department of Defense's Long-Term Impact of Military-Relevant Brain Injury Consortium-Chronic Effects of Neurotrauma Consortium (LIMBIC-CENC).
(Copyright © 2023, McLoughlin et al.)
Databáze: MEDLINE