Medullary brainstem gliomas in an adult: A rare case report and challenging tumor.

Autor: Aleid AM; Department of Neurosurgery, King Faisal Univeristy, Ahsa, Saudi Arabia., Alaethan MH; Department of Neurosurgery, King Faisal Univeristy, Ahsa, Saudi Arabia., Alsaati AA; Department of Neurosurgery, King Faisal Univeristy, Ahsa, Saudi Arabia., Alhejji MH; Department of Radiology, King Saud bin Abdulaziz University - Health Science, Ahsa, Saudi Arabia., Ali Alkathem J; Department of Neurosurgery, King Faisal Univeristy, Ahsa, Saudi Arabia.
Jazyk: angličtina
Zdroj: Surgical neurology international [Surg Neurol Int] 2023 Jun 02; Vol. 14, pp. 190. Date of Electronic Publication: 2023 Jun 02 (Print Publication: 2023).
DOI: 10.25259/SNI_189_2023
Abstrakt: Background: Medullary brainstem lesions are rare tumors that are challenging to treat due to their location in the brainstem, which controls vital functions such as breathing, heart rate, and blood pressure. While the most common subtype is the aggressive diffuse intrinsic pontine glioma, other subtypes exist, including focal brainstem gliomas and cervicomedullary gliomas. The prognosis for patients with brainstem gliomas is generally poor, and treatment options are limited. Early detection and treatment are crucial to improve outcomes for patients with these tumors.
Case Description: In this case report, the authors describe a 28-year-old male from Saudi Arabia who presented with headaches and vomiting. Imaging studies and clinical examination revealed a high-grade astrocytoma medullary brainstem lesion. The patient underwent radiation therapy and chemotherapy, effectively controlling tumor growth and improving his quality of life. However, a residual tumor remained, and the patient underwent neurosurgery to resect the remaining tumor was successful in removing the tumor, and the patient showed significant improvement in his symptoms and overall health.
Conclusion: This case highlights the importance of early detection and treatment of medullary brainstem lesions. While radiation therapy and chemotherapy are primary treatment options, neurosurgery may be necessary to resect residual tumors. In addition, cultural and social factors may need to be considered in managing these tumors in Saudi Arabia.
Competing Interests: There are no conflicts of interest.
(Copyright: © 2023 Surgical Neurology International.)
Databáze: MEDLINE