The effect of body size and composition on lumbar spine trabecular bone score in morphologically diverse subjects.

Autor: Malczewska-Lenczowska J; Department of Nutrition Physiology and Dietetics, Institute of Sport-National Research Institute, Warsaw, Poland., Surała O; Department of Nutrition Physiology and Dietetics, Institute of Sport-National Research Institute, Warsaw, Poland., Sitkowski D; Department of Physiology, Institute of Sport-National Research Institute, Warsaw, Poland., Szczepańska B; Department of Nutrition Physiology and Dietetics, Institute of Sport-National Research Institute, Warsaw, Poland., Zawadzki M; High School of Rehabilitation, Warsaw, Poland.
Jazyk: angličtina
Zdroj: PloS one [PLoS One] 2023 Jul 03; Vol. 18 (7), pp. e0287330. Date of Electronic Publication: 2023 Jul 03 (Print Publication: 2023).
DOI: 10.1371/journal.pone.0287330
Abstrakt: Aim: The trabecular bone score (TBS) is a tool for assessing bone quality and health. Current TBS algorithm corrects for body mass index (BMI), as a proxy of regional tissue thickness. However, this approach fails to consider BMI inaccuracies due to individual differences in body stature, composition and somatotype. This study investigated the relationship between TBS and body size and composition in subjects with a normal BMI, but with large morphological diversity in body fatness and height.
Methods: Young male subjects (n = 97; age 17.2±1.0 years), including ski jumpers (n = 25), volleyball players (n = 48) and non-athletes (controls n = 39), were recruited. The TBS was determined from L1-L4 dual-energy X-ray absorptiometry (DXA) scans using TBSiNsight software.
Results: TBS correlated negatively with height and tissue thickness in the L1-L4 area in ski jumpers (r = -0.516 and r = -0.529), volleyball players (r = -0.525 and r = -0.436), and the total group (r = -0.559 and r = -0.463), respectively. Multiple regression analyses revealed that height, L1-L4 soft tissue thickness, fat mass and muscle mass were significant determinants of TBS (R2 = 0.587, p<0.001). L1-L4 soft tissue thickness explained 27% and height 14% of the TBS variance.
Conclusion: The negative association of TBS and both features suggests that a very low L1-L4 tissue thickness may lead to overestimation of the TBS, while tall stature may have the opposite effect. It seems that the utility of the TBS as a skeletal assessment tool in lean and/or tall young male subjects could be improved if tissues thickness in the lumbar spine area and stature instead of BMI were considered in the algorithm.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright: © 2023 Malczewska-Lenczowska et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
Databáze: MEDLINE
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