A case of cutaneous psoriasis vulgaris achieving complete remission post major breast reconstructive surgery.

Autor: Ngiam EHK; General Surgery, Sengkang General Hospital, Singapore., Fok D; Plastic and Aesthetic Reconstructive Surgery, Sengkang General Hospital, Singapore., Sim N; Plastic and Aesthetic Reconstructive Surgery, Sengkang General Hospital, Singapore., Wong A; Plastic and Aesthetic Reconstructive Surgery, Sengkang General Hospital, Singapore., Feng J; Plastic and Aesthetic Reconstructive Surgery, Sengkang General Hospital, Singapore., Pearlie T; Plastic and Aesthetic Reconstructive Surgery, Sengkang General Hospital, Singapore., Chua HW; General Surgery, Sengkang General Hospital, Singapore., Chan G; Rheumatology, Tan Tock Seng Hospital, Singapore., Kok YO; Plastic and Aesthetic Reconstructive Surgery, Sengkang General Hospital, Singapore.
Jazyk: angličtina
Zdroj: Journal of surgical case reports [J Surg Case Rep] 2023 Jun 28; Vol. 2023 (6), pp. rjad148. Date of Electronic Publication: 2023 Jun 28 (Print Publication: 2023).
DOI: 10.1093/jscr/rjad148
Abstrakt: Psoriasis is a debilitating chronic inflammatory systemic condition largely affecting the skin. Major surgery is relatively contraindicated due to the propensity for triggering psoriatic flares and koebnerization of the surgical scars. We detail an interesting case of complete psoriasis remission following a right nipple-sparing mastectomy with sentinel lymph node biopsy with vascular augmented pedicled transverse rectus abdominal myocutaneous (TRAM) flap in a patient with systemic psoriasis vulgaris and arthropathy. Intra-operatively, majority of the psoriatic plaques were excised or de-epithelized and used as part of the ipsilateral TRAM flap. Post-operatively, koebnerization did not occur and her psoriasis was cured completely even after cancer chemotherapy. One of several hypotheses include excision with de-epithelization of most of the psoriatic plaques reduces disease and inflammatory burden leading to complete remission. Perhaps, surgery could one day play a supporting role to existing treatment options to achieve psoriasis remission.
Competing Interests: None declared.
(Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2023.)
Databáze: MEDLINE
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