Antibiotic utilization in endoscopic dacryocystorhinostomy: a multi-institutional study and review of the literature.

Autor:	Boal NS; Department of Ophthalmology, Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts, USA., Chiou CA; Division of Ophthalmic Plastic Surgery, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, USA.; Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, USA., Sadlak N; Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, USA., Sarmiento VA; Department of Ophthalmology, Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts, USA., Lefebvre DR; Division of Ophthalmic Plastic Surgery, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, USA.; Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, USA.; Division of Ophthalmology, Surgical Service, Boston Veterans Affairs HealthCare System, Boston, Massachusetts, USA.; Dedham Ophthalmic Consultants and Surgeons / Lexington Eye Associates, Dedham, Massachusetts, USA., Distefano AG; Department of Ophthalmology, Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts, USA.
Jazyk:	angličtina
Zdroj:	Orbit (Amsterdam, Netherlands) [Orbit] 2024 Apr; Vol. 43 (2), pp. 183-189. Date of Electronic Publication: 2023 Jul 03.
DOI:	10.1080/01676830.2023.2227705
Abstrakt:	Purpose: Utilization of antibiotics for endoscopic dacryocystorhinostomy (endo-DCR) is largely dependent on individual surgeon preference. This study aimed to investigate prescribing practices of pre-, peri-, and postoperative antibiotics and effects on postoperative infection rates in patients who underwent endo-DCR. Methods: A retrospective chart review of institutional data at two academic centers of endo-DCR cases from 2015-2020 was performed. Postoperative infection rates for patients who received pre-, peri-, and postoperative antibiotics, individually or in combination, and those who did not, were compared via odds ratio and ANOVA linear regression. Results: 331 endo-DCR cases were included; 22 cases (6.6%) had a postoperative infection. There was no significant difference in the infection rates between patients without an active preoperative dacryocystitis who received different permutations of peri- and postoperative antibiotics. Patients who received preoperative antibiotics within two weeks of surgery for preexisting acute dacryocystitis, but did not receive peri- or postoperative antibiotics, had a higher rate of postoperative infections ( p  = 008). Conclusions: Our data suggest antibiotics may be beneficial only when patients have a recent or active dacryocystitis prior to surgery. Otherwise, our data do not support the routine use of antibiotic prophylaxis in endo-DCR.
Databáze:	MEDLINE
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