Diagnostic and Cost Efficiency of the 0-h/1-h Rule-out and Rule-in Algorithm for Patients With Chest Pain in the Emergency Department.

Autor:	Sasaki S; Department of Cardiovascular Biology and Medicine, Juntendo University Nerima Hospital., Inoue K; Department of Cardiovascular Biology and Medicine, Juntendo University Nerima Hospital., Shiozaki M; Department of Cardiology, Tokyo Metropolitan Tama Medical Center., Hanada K; Crecon Medical Assessment Inc., Watanabe R; Graduate School of Health Innovation, Kanagawa University of Human Service., Minamino T; Department of Cardiovascular Biology and Medicine, Juntendo University School of Medicine.
Jazyk:	angličtina
Zdroj:	Circulation journal : official journal of the Japanese Circulation Society [Circ J] 2023 Sep 25; Vol. 87 (10), pp. 1362-1368. Date of Electronic Publication: 2023 Jun 30.
DOI:	10.1253/circj.CJ-23-0064
Abstrakt:	Background: This study investigated the economic impact of the European Society of Cardiology (ESC) clinical practice guideline recommendation of using the 0-h/1-h rule-out and rule-in algorithm with high-sensitivity cardiac troponin assays (0/1-h algorithm) to triage patients presenting with chest pain. Methods and results: This post hoc cost-effectiveness evaluation (DROP-ACS; UMIN000030668) used deidentified electronic medical records from health insurance claims from 2 diagnostic centers in Japan. A cost-effectiveness analysis was conducted with 472 patients with care provided following the 0/1-h algorithm (Hospital A) and 427 patients following point-of-care testing (Hospital B). The clinical outcome of interest was all-cause mortality or subsequent myocardial infarction within 30 days of the index presentation. The sensitivity and specificity for the clinical outcome were 100% (95% confidence interval [CI] 91.1-100%) and 95.0% (95% CI 94.3-95.0%), respectively, in Hospital A and 92.9% (95% CI 69.6-98.7%) and 89.8% (95% CI 89.0-90.0%), respectively, in Hospital B. If the diagnostic accuracy of the 0/1-h algorithm was implemented in Hospital B, it is expected that the number of urgent (<24-h) coronary angiograms would decrease by 50%. Incorporating this assumption, implementing the 0/1-h algorithm could potentially reduce medical costs by JPY4,033,874 (95% CI JPY3,440,346-4,627,402) in Hospital B (JPY9,447 per patient; 95% CI JPY 8,057-10,837 per patient). Conclusions: The ESC 0/1-h algorithm was efficient for risk stratification and for reducing medical costs.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu