Encapsulation into hyaluronic acid-based nanogels improves the selectivity index of the snake cathelicidin Ab-Cath.

Autor: van Gent ME; Department of Infectious Diseases, Leiden University Medical Center, 2300 RC Leiden, the Netherlands. Electronic address: M.E.van_Gent@lumc.nl., Kłodzińska SN; Center for Biopharmaceuticals and Biobarriers in Drug Delivery (BioDelivery), Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark., Severin M; Department of Infectious Diseases, Leiden University Medical Center, 2300 RC Leiden, the Netherlands., Ali M; Department of Infectious Diseases, Leiden University Medical Center, 2300 RC Leiden, the Netherlands., van Doodewaerd BR; Department of Cell and Chemical Biology, Leiden University Medical Center, 2300 RC Leiden, the Netherlands., Bos E; Electron Microscopy Facility, Department of Cell and Chemical Biology, Leiden University Medical Center, 2300 RC Leiden, the Netherlands., Koning RI; Electron Microscopy Facility, Department of Cell and Chemical Biology, Leiden University Medical Center, 2300 RC Leiden, the Netherlands., Drijfhout JW; Department of Immunology, Leiden University Medical Center, 2300 RC Leiden, the Netherlands., Nielsen HM; Center for Biopharmaceuticals and Biobarriers in Drug Delivery (BioDelivery), Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark., Nibbering PH; Department of Infectious Diseases, Leiden University Medical Center, 2300 RC Leiden, the Netherlands.
Jazyk: angličtina
Zdroj: Nanomedicine : nanotechnology, biology, and medicine [Nanomedicine] 2023 Aug; Vol. 52, pp. 102694. Date of Electronic Publication: 2023 Jun 30.
DOI: 10.1016/j.nano.2023.102694
Abstrakt: Competing Interests: Declaration of competing interest The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results
Databáze: MEDLINE
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