Acceptability of a Combination Adherence Strategy to Support HIV Antiretroviral Therapy and Pre-exposure Prophylaxis Adherence During Pregnancy and Breastfeeding in Malawi.

Autor: Saidi F; University of North Carolina (UNC) Project Malawi, Bag A-104, Lilongwe, Malawi. fsaidi@unclilongwe.org.; Department of Obstetrics and Gynecology, Kamuzu University of Health Sciences, Lilongwe, Malawi. fsaidi@unclilongwe.org.; Department of Obstetrics and Gynecology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. fsaidi@unclilongwe.org., Phanga T; University of North Carolina (UNC) Project Malawi, Bag A-104, Lilongwe, Malawi., Graybill LA; Department of Epidemiology, University of North Carolina at Chapel Hill Gillings School of Global Public Health, Chapel Hill, NC, USA., Mollan KR; Department of Epidemiology, University of North Carolina at Chapel Hill Gillings School of Global Public Health, Chapel Hill, NC, USA., Hill LM; Department of Health Behavior, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Sibande W; University of North Carolina (UNC) Project Malawi, Bag A-104, Lilongwe, Malawi., Msowoya G; University of North Carolina (UNC) Project Malawi, Bag A-104, Lilongwe, Malawi., Thom A; University of North Carolina (UNC) Project Malawi, Bag A-104, Lilongwe, Malawi., Rosenberg NE; Department of Health Behavior, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Freeborn K; Department of Obstetrics and Gynecology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Amico KR; Department of Health Behavior and Health Education, University of Michigan School of Public Health, Ann Arbor, MI, USA., Phiri S; Partners in Hope, Lilongwe, Malawi., Mutale W; Department of Health Policy, University of Zambia School of Public Health, Lusaka, Zambia., Chi BH; Department of Obstetrics and Gynecology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Jazyk: angličtina
Zdroj: AIDS and behavior [AIDS Behav] 2023 Dec; Vol. 27 (12), pp. 4022-4032. Date of Electronic Publication: 2023 Jul 01.
DOI: 10.1007/s10461-023-04116-x
Abstrakt: In two parallel pilot studies, we implemented a combination adherence intervention of patient-centered counselling and adherence supporter training, tailored to support HIV treatment (i.e., antiretroviral therapy) or prevention (i.e., pre-exposure prophylaxis, or PrEP) during pregnancy and breastfeeding. Using a mixed-methods approach, we evaluated the intervention's acceptability. We investigated engagement, satisfaction, and discussion content via survey to all 151 participants assigned to the intervention arm (51 women living with HIV, 100 PrEP-eligible women without HIV). We also conducted serial in-depth interviews with a subgroup (n = 40) at enrollment, three months, and six months. In the quantitative analysis, the vast majority reported high satisfaction with intervention components and expressed desire to receive it in the future, if made available. These findings were supported in the qualitative analysis, with favorable comments about counselor engagement, intervention content and types of support received from adherence supporters. Overall, these results demonstrate high acceptability and provide support for HIV status-neutral interventions for antiretroviral adherence.
(© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
Databáze: MEDLINE
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