Maternal weight and its association with risk of overweight in offspring: a trajectory analysis from a birth cohort in China.

Autor: Deng R; Institute of Child and Adolescent Health, School of Public Health, Peking University Health Science Center, No.38 Xueyuan Rd, Haidian District, Beijing, 100191, China., Li WQ; Tianjin Women and Children's Health Center, No. 96 Guizhou Rd, Heping District, Tianjin, 300070, China., Li XX; Institute of Child and Adolescent Health, School of Public Health, Peking University Health Science Center, No.38 Xueyuan Rd, Haidian District, Beijing, 100191, China., Wei LM; Institute of Child and Adolescent Health, School of Public Health, Peking University Health Science Center, No.38 Xueyuan Rd, Haidian District, Beijing, 100191, China., Hu J; Menzies Health Institute Queensland, Griffith University, Nathan, QLD, 4111, Australia., Leng JH; Tianjin Women and Children's Health Center, No. 96 Guizhou Rd, Heping District, Tianjin, 300070, China. ljhlzqljhlzq@163.com., Dong B; Institute of Child and Adolescent Health, School of Public Health, Peking University Health Science Center, No.38 Xueyuan Rd, Haidian District, Beijing, 100191, China. bindong@bjmu.edu.cn.
Jazyk: angličtina
Zdroj: World journal of pediatrics : WJP [World J Pediatr] 2024 May; Vol. 20 (5), pp. 496-505. Date of Electronic Publication: 2023 Jun 30.
DOI: 10.1007/s12519-023-00736-4
Abstrakt: Background: Most studies on the association of maternal pregnancy weight with offspring weight trajectory have a short follow-up time. This study aimed to explore the associations of maternal prepregnancy body mass index (BMI) and gestational weight gain (GWG) with childhood weight trajectories in a 7-year birth cohort.
Methods: A total of 946 mother-child pairs (467 boys and 479 girls) from a longitudinal birth cohort in Tianjin City, China, were included in this study, ranging from pregnancy to offspring at 7 years. The outcome variable was defined as overweight or not overweight in offspring at the last round. A group-based trajectory model was applied to identify childhood BMI trajectory groups.
Results: Five discrete BMI trajectory groups were identified and characterized as constant underweight (25.2%), constant normal weight (42.8%), and high or increasing trajectory [at risk of overweight (16.9%), progressive overweight (11.0%) and progressive obesity (4.1%)]. Maternal prepregnancy overweight was associated with 1.72 (95% CI 1.14-2.60, P = 0.01) to 4.02 (95% CI 1.94-8.36, P < 0.001) times the risk of all high or increasing trajectory groups, and excessive GWG was related to groups at risk of overweight [relative risk ratio (RRR) 2.09, 95% CI 1.27-3.46, P = 0.004] and progressive obesity (RRR 3.33, 95% CI 1.13-9.79, P = 0.029). Children in all high or increasing trajectory groups were associated with greater overweight risk at the last round [risk ratios (RRs) ranged from 3.54 (95% CI 2.53-4.95, P < 0.001) to 6.18 (95% CI 4.05-9.42, P < 0.001)].
Conclusion: Maternal prepregnancy overweight and excessive gestational weight gain were associated with increasing or high-level childhood body mass index trajectories as well as a greater risk of overweight at 7 years.
(© 2023. Children's Hospital, Zhejiang University School of Medicine.)
Databáze: MEDLINE
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