fMRI with whole-brain coverage, 75-ms temporal resolution and high SNR by combining HiHi reshuffling and multiband imaging.

Autor: Schmidt T; Laboratory for Social and Neural Systems Research, University of Zurich, Zurich, Switzerland; Institute for Biomedical Engineering, ETH Zurich and University of Zurich, Zurich, Switzerland. Electronic address: tim.schmidt@econ.uzh.ch., Vannesjo SJ; Department of Physics, Norwegian University of Science and Technology, Trondheim, Norway., Sommer S; Siemens Healthineers International AG, Zurich, Switzerland; Swiss Center for Musculoskeletal Imaging (SCMI), Balgrist Campus, Zurich, Switzerland; Advanced Clinical Imaging Technology (ACIT), Siemens Healthineers International AG, Lausanne, Switzerland., Nagy Z; Laboratory for Social and Neural Systems Research, University of Zurich, Zurich, Switzerland.
Jazyk: angličtina
Zdroj: Magnetic resonance imaging [Magn Reson Imaging] 2023 Nov; Vol. 103, pp. 48-53. Date of Electronic Publication: 2023 Jun 27.
DOI: 10.1016/j.mri.2023.06.015
Abstrakt: Increasing the temporal resolution of the blood‑oxygen level-dependent (BOLD) response is usually accompanied by a decrease in repetition time and therefore also a reduction of the magnetic resonance (MR) signal due to incomplete T1 relaxation and thus a loss of signal-to-noise ratio (SNR). A previous data reordering method can achieve higher temporal sampling rate without the loss of SNR but at the cost of increased scan time. In this proof-of-principle work, we show that combining HiHi reshuffling with multiband acceleration allows us to measure the in vivo BOLD response with a 75-ms sampling rate that is decoupled from the acquisition repetition time (here 1.5 s and hence higher SNR) while covering the entire forebrain with 60 2-mm slices in a ~ 35-min scan. We provide single-voxel time-courses of the BOLD responses in the primary visual and primary motor cortices in three fMRI experiments on a 7 T scanner - 1 male (scanned twice on different days for test-retest reproducibility) and 1 female participant.
Competing Interests: Declaration of Competing Interest The authors have no competing interest to declare.
(Copyright © 2023 The Authors. Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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