Optimal Frequency of Hepatitis C Virus (HCV) RNA Testing for Detection of Acute HCV Infection Among At-risk People With Human Immunodeficiency Virus: A Multicenter Study.

Autor: Sun HY; Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan., Liou BH; Department of Internal Medicine, Hsinchu MacKay Memorial Hospital, Hsinchu, Taiwan., Chen TC; Department of Internal Medicine, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung, Taiwan.; Department of Internal Medicine, Kaohsiung Medical University Hospital and College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan., Yang CJ; Department of Internal Medicine, Far Eastern Memorial Hospital, New Taipei City, Taiwan.; School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan., Huang SH; Department of Internal Medicine, National Taiwan University Hospital Hsin-Chu Branch, Hsinchu, Taiwan.; Department of Tropical Medicine and Parasitology, National Taiwan University College of Medicine, Taipei, Taiwan., Lu PL; Department of Internal Medicine, Kaohsiung Medical University Hospital and College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan., Huang CH; Department of Internal Medicine, Kaohsiung Medical University Hospital and College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan., Tsai MS; Department of Internal Medicine, Far Eastern Memorial Hospital, New Taipei City, Taiwan., Cheng SH; Department of Infectious Diseases, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan.; School of Public Health, Taipei Medical University, Taipei, Taiwan., Lee NY; Department of Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan., Ko WC; Department of Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan., Chen YH; School of Medicine, College of Medicine, National Sun Yat-Sen University, Kaohsiung, Taiwan., Liu WD; Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.; Department of Internal Medicine, National Taiwan University Cancer Center, Taipei, Taiwan., Lin SY; Department of Internal Medicine, Kaohsiung Medical University Hospital and College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan., Lin SP; Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan., Chen PL; Department of Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan., Syue LS; Department of Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan., Huang YS; Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan., Chuang YC; Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan., Chen CB; Department of Infectious Diseases, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan., Chang YT; Department of Internal Medicine, Kaohsiung Medical University Hospital and College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan., Lee YT; Department of Internal Medicine, Chung Shan Medical University Hospital, Taichung, Taiwan.; School of Medicine, Chung Shan Medical University, Taichung, Taiwan., Hsieh SM; Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan., Su LH; Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan., Cheng CY; Department of Infectious Diseases, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan.; School of Public Health, National Yang Ming Chiao Tung University, Taipei, Taiwan., Hung CC; Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.; Department of Tropical Medicine and Parasitology, National Taiwan University College of Medicine, Taipei, Taiwan.; Department of Internal Medicine, National Taiwan University Hospital Yun-Lin Branch, Yun-Lin, Taiwan.
Jazyk: angličtina
Zdroj: Open forum infectious diseases [Open Forum Infect Dis] 2023 Jun 06; Vol. 10 (6), pp. ofad307. Date of Electronic Publication: 2023 Jun 06 (Print Publication: 2023).
DOI: 10.1093/ofid/ofad307
Abstrakt: Using 3-stage pooled-plasma hepatitis C virus (HCV) RNA testing performed quarterly among at-risk people with human immunodeficiency virus (PWH), we found that if testing had been performed every 6 or 12 months, 58.6%-91.7% of PWH who recently acquired HCV would be delayed for diagnosis and might contribute to onward HCV transmission with longer durations.
Competing Interests: Potential conflicts of interest. C.-C. H. has received research support from Gilead Sciences and speaker honoraria from Gilead Sciences, and served on advisory boards for Gilead Sciences. H.-Y. S. has received research support from Gilead Sciences. Other authors have no competing interest to disclose.
(© The Author(s) 2023. Published by Oxford University Press on behalf of Infectious Diseases Society of America.)
Databáze: MEDLINE
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