Clinical Outcomes and Laboratory Values of Infants with COVID-19 among Several Maternal Variables: A Retrospective Cohort.

Autor:	Bechor Ariel T; Department of Pediatrics, Sanz Medical Center-Laniado Hospital, Netanya, Israel, Adelson School of Medicine, Ariel University, Ariel, Israel., Ariel B; Department of Pediatrics, Sanz Medical Center-Laniado Hospital, Netanya, Israel, Adelson School of Medicine, Ariel University, Ariel, Israel., Lahav Y; Department of Pediatrics, Sanz Medical Center-Laniado Hospital, Netanya, Israel, Adelson School of Medicine, Ariel University, Ariel, Israel., Yana M; Department of Pediatrics, Sanz Medical Center-Laniado Hospital, Netanya, Israel, Adelson School of Medicine, Ariel University, Ariel, Israel., Ben-Acon M; Department of Pediatrics, Sanz Medical Center-Laniado Hospital, Netanya, Israel, Adelson School of Medicine, Ariel University, Ariel, Israel., Sharon N; Department of Pediatrics, Sanz Medical Center-Laniado Hospital, Netanya, Israel, Adelson School of Medicine, Ariel University, Ariel, Israel.
Jazyk:	angličtina
Zdroj:	The Israel Medical Association journal : IMAJ [Isr Med Assoc J] 2023 Jun; Vol. 25 (6), pp. 387-391.
Abstrakt:	Background: Infants younger than 6 months of age are not eligible for coronavirus disease 2019 (COVID-19) vaccinations. Maternal variables during pregnancy and the postnatal period may affect the clinical and laboratory course of COVID-19 positive infants. Objectives: To assess the clinical manifestation and laboratory differences in infants with three maternal variables: breastfeeding, vaccinated, and co-illness. Methods: We conducted a single-center retrospective cohort study of positive COVID-19 infants with three subgroups of maternal variables. The population included infants under 6 months of age hospitalized due to COVID-19. Data about clinical features, laboratory tests, and maternal information including vaccination status, breastfeeding status and maternal positive COVID-19 infection was gathered. All variables were compared among the three subgroups. Results: Breastfed infants had shorter hospitalization period (mean 2.61 ± 1.378 days) compared to non-breastfed infants (mean 3.8 ± 1.549) (P = 0.051). COVID-19 infants of positive COVID-19 mothers had a higher absolute neutrophil count (mean 4.4 ± 3.8) compared to infants of COVID-19 negative mothers (mean 2.7 ± 2.4) (P = 0.042). Conclusions: Breastfeeding was associated with shorter periods of hospitalization in COVID-19 positive infants. In addition, positive COVID-19 infants of mothers who were positive for COVID-19 are likely to have a higher absolute neutrophils count.
Databáze:	MEDLINE
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