The Clinical Spectrum and Manifestations of Acute-on-Chronic Liver Failure.
| Autor: | Scheinberg AR; Division of Digestive Health and Liver Diseases, University of Miami Miller School of Medicine, Miami, 1120 Northwest 14th Street, Miami, FL 33136, USA., Martin P; Division of Digestive Health and Liver Diseases, University of Miami Miller School of Medicine, Miami, 1120 Northwest 14th Street, Miami, FL 33136, USA. Electronic address: pmartin2@med.miami.edu., Bhamidimarri KR; Division of Digestive Health and Liver Diseases, University of Miami Miller School of Medicine, Miami, 1120 Northwest 14th Street, Miami, FL 33136, USA. |
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| Jazyk: | angličtina |
| Zdroj: | Clinics in liver disease [Clin Liver Dis] 2023 Aug; Vol. 27 (3), pp. 671-680. Date of Electronic Publication: 2023 Apr 23. |
| DOI: | 10.1016/j.cld.2023.03.010 |
| Abstrakt: | Acute-on-chronic liver failure (ACLF) is characterized by abrupt decompensation in a patient with chronic liver disease with extrahepatic organ dysfunction and is implicated in an increased risk of mortality. ACLF may be present in approximately 20% to 40% of hospitalized cirrhosis. There are several diagnostic scoring systems for ACLF; one defined by the North American Consortium for Study of End-stage Liver Disease is the presence of acutely decompensated cirrhosis complicated by failure of two or more organ systems: circulatory, renal, neurological, coagulopathy, and/or pulmonary. (Copyright © 2023 Elsevier Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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