Pathology of Acute and Acute-on-Chronic Liver Failure.
| Autor: | Beech C; Department of Pathology, ARUP Laboratories, University of Utah, Salt Lake City, UT 84112, USA., Liu C; Department of Pathology, Yale School of Medicine, New Haven, CT 06520-8023, USA. Electronic address: chen.liu@yale.edu., Zhang X; Department of Pathology, Yale School of Medicine, New Haven, CT 06520-8023, USA. Electronic address: xuchen.zhang@yale.edu. |
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| Jazyk: | angličtina |
| Zdroj: | Clinics in liver disease [Clin Liver Dis] 2023 Aug; Vol. 27 (3), pp. 581-593. Date of Electronic Publication: 2023 Apr 23. |
| DOI: | 10.1016/j.cld.2023.03.004 |
| Abstrakt: | Liver failure can develop as either acute liver failure in the absence of preexisting liver disease, or as acute-on-chronic liver failure in a patient with underlying chronic liver disease or cirrhosis. A timely liver biopsy is helpful to distinguish acute and chronic liver disease, identify precipitating factors, provide prognostic information based on pathologic changes, and aid in making appropriate decisions for patient management. This article will discuss the pathologic features of acute and acute-on-chronic liver failure. Developing an appreciation for the histopathologic patterns of injury observed in these entities is essential for a practical understanding of the diagnostic process. (Copyright © 2023 Elsevier Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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