Concordance of Ethyl Glucuronide, Blood Alcohol Content, and Self-Reported Alcohol Use in Russian Women with HIV and Hepatitis C Virus Co-Infection.

Autor: Brown JL; Department of Psychological Sciences, Purdue University, 703 3rd Street, Room 1242, West Lafayette, IN, 47907, USA. jenniferbrown@purdue.edu., Capasso A; Health Resources in Action, Boston, MA, USA., Revzina N; U.S. Centers for Disease Control and Prevention, Atlanta, GA, USA., Boeva E; First Saint Petersburg State Pavlov Medical University, Saint Petersburg, Russia.; Saint Petersburg Pasteur Institute, Saint Petersburg, Russia., Rassokhin V; First Saint Petersburg State Pavlov Medical University, Saint Petersburg, Russia.; Saint Petersburg Pasteur Institute, Saint Petersburg, Russia., Sales JM; Department of Behavioral, Social, and Health Education Sciences, Rollins School of Public Health, Emory University, Atlanta, GA, USA., Gutova LV; First Saint Petersburg State Pavlov Medical University, Saint Petersburg, Russia., Khalezova NB; First Saint Petersburg State Pavlov Medical University, Saint Petersburg, Russia., Hitch AE; Department of Psychology, University of Cincinnati, Cincinnati, OH, USA., Twitty TD; Department of Psychology, University of Cincinnati, Cincinnati, OH, USA., DiClemente RJ; Department of Social and Behavioral Sciences, School of Global Public Health, New York University, New York, NY, USA.
Jazyk: angličtina
Zdroj: AIDS and behavior [AIDS Behav] 2023 Dec; Vol. 27 (12), pp. 4062-4069. Date of Electronic Publication: 2023 Jun 28.
DOI: 10.1007/s10461-023-04120-1
Abstrakt: Problematic alcohol use is prevalent in Russia and is deleterious for individuals with HIV and Hepatitis C Virus (HCV). Ethyl glucuronide (EtG) and blood alcohol content (BAC) provide objective biomarkers of drinking that can be compared to self-reported alcohol use. This paper describes patterns of alcohol use measured by biomarkers and self-report along with concordance across measures. Participants were Russian women with HIV and HCV co-infection (N = 200; Mean age = 34.9) from two Saint Petersburg comprehensive HIV care centers enrolled in an alcohol reduction intervention clinical trial. Measures were: (a) urine specimen analyzed for EtG; (b) breathalyzer reading of BAC; and (c) self-reported frequency of drinking, typical number of drinks consumed, and number of standard drinks consumed in the past month. At baseline, 64.0% (n = 128) had a positive EtG (> 500 ng/mL) and 76.5% (n = 153) had a positive breathalyzer reading (non-zero reading). There was agreement between EtG and BAC (kappa = 0.66, p < .001; Phi coefficient = 0.69, p < .001); self-reported alcohol measures were positively correlated with positive EtG and BAC (p's < 0.001). There was concordance between EtG and BAC measures, which have differing alcohol detection windows. Most participants endorsed frequent drinking at high quantities, with very few reporting no alcohol consumption in the past month. Concordance between biomarkers and self-reported alcohol use suggests that underreporting of alcohol use was minimal. Results highlight the need for alcohol screening within HIV care. Implications for alcohol assessment within research and clinical contexts are discussed.
(© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
Databáze: MEDLINE
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