Disseminated Nocardia farcinica infection associated with bacteraemia and osteomyelitis pubis in an elderly patient.

Autor: Fernández Vecilla D; Clinical Microbiology Service, Laredo Regional Hospital, Laredo, Cantabria, Spain., Roche Matheus MP; Clinical Microbiology Service, Basurto University Hospital, Bilbao, Biscay, Spain.; Biocruces Bizkaia Health Research Institute, Biscay, Spain., Urrutikoetxea Gutiérrez MJ; Clinical Microbiology Service, Basurto University Hospital, Bilbao, Biscay, Spain.; Biocruces Bizkaia Health Research Institute, Biscay, Spain., Calvo Muro FE; Clinical Microbiology Service, Basurto University Hospital, Bilbao, Biscay, Spain.; Biocruces Bizkaia Health Research Institute, Biscay, Spain., Aspichueta Vivanco C; Clinical Microbiology Service, Basurto University Hospital, Bilbao, Biscay, Spain.; Biocruces Bizkaia Health Research Institute, Biscay, Spain., López Azkarreta I; Infectious Diseases Service of Basurto University Hospital, Bilbao, Biscay, Spain., Grau García M; Radiodiagnosis Service of Basurto University Hospital, Bilbao, Biscay, Spain., Díaz de Tuesta Del Arco JL; Clinical Microbiology Service, Basurto University Hospital, Bilbao, Biscay, Spain.; Biocruces Bizkaia Health Research Institute, Biscay, Spain.
Jazyk: angličtina
Zdroj: Infectious diseases (London, England) [Infect Dis (Lond)] 2023 Oct; Vol. 55 (10), pp. 738-743. Date of Electronic Publication: 2023 Jun 28.
DOI: 10.1080/23744235.2023.2229425
Abstrakt: Objective: We describe a rare case of a disseminated Nocardia farcinica infection associated with hip osteomyelitis.
Methods: A 91-year-old female patient was admitted with oedema of her right leg, fever of 38 °C and data consistent with ruptured Baker's cyst. A disseminated Nocardia farcinica infection including bloodstream infection, pneumonia and multiple abscesses along both lower limbs was observed.
Results: After a four-week course of 320 mg / 1600 mg/12 h of intravenous trimethoprim/sulfamethoxazole and multiple chirurgic drainages the patient was discharged with oral trimethoprim/sulfamethoxazole. Nevertheless, the patient expired done month after being discharged from the hospital.
Conclusions: The implementation of a combination of intravenous antibiotics and drainages resulted in an initial improvement in the patient's condition. However, despite these interventions, the patient ultimately passed away probably due to natural causes.
Databáze: MEDLINE
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