Therapeutic Perspectives for Microbiota Transplantation in Digestive Diseases and Neoplasia-A Literature Review.

Autor:	Boicean A; County Clinical Emergency Hospital of Sibiu, 550245 Sibiu, Romania.; Faculty of Medicine, Lucian Blaga University of Sibiu, 550169 Sibiu, Romania., Bratu D; County Clinical Emergency Hospital of Sibiu, 550245 Sibiu, Romania.; Faculty of Medicine, Lucian Blaga University of Sibiu, 550169 Sibiu, Romania., Bacila C; Faculty of Medicine, Lucian Blaga University of Sibiu, 550169 Sibiu, Romania., Tanasescu C; County Clinical Emergency Hospital of Sibiu, 550245 Sibiu, Romania.; Faculty of Medicine, Lucian Blaga University of Sibiu, 550169 Sibiu, Romania., Fleacă RS; County Clinical Emergency Hospital of Sibiu, 550245 Sibiu, Romania.; Faculty of Medicine, Lucian Blaga University of Sibiu, 550169 Sibiu, Romania., Mohor CI; County Clinical Emergency Hospital of Sibiu, 550245 Sibiu, Romania.; Faculty of Medicine, Lucian Blaga University of Sibiu, 550169 Sibiu, Romania., Comaniciu A; County Clinical Emergency Hospital of Sibiu, 550245 Sibiu, Romania., Băluță T; County Clinical Emergency Hospital of Sibiu, 550245 Sibiu, Romania., Roman MD; County Clinical Emergency Hospital of Sibiu, 550245 Sibiu, Romania.; Faculty of Medicine, Lucian Blaga University of Sibiu, 550169 Sibiu, Romania., Chicea R; County Clinical Emergency Hospital of Sibiu, 550245 Sibiu, Romania.; Faculty of Medicine, Lucian Blaga University of Sibiu, 550169 Sibiu, Romania., Cristian AN; County Clinical Emergency Hospital of Sibiu, 550245 Sibiu, Romania.; Faculty of Medicine, Lucian Blaga University of Sibiu, 550169 Sibiu, Romania., Hasegan A; County Clinical Emergency Hospital of Sibiu, 550245 Sibiu, Romania.; Faculty of Medicine, Lucian Blaga University of Sibiu, 550169 Sibiu, Romania., Birsan S; County Clinical Emergency Hospital of Sibiu, 550245 Sibiu, Romania.; Faculty of Medicine, Lucian Blaga University of Sibiu, 550169 Sibiu, Romania., Dura H; County Clinical Emergency Hospital of Sibiu, 550245 Sibiu, Romania.; Faculty of Medicine, Lucian Blaga University of Sibiu, 550169 Sibiu, Romania., Mohor CI; County Clinical Emergency Hospital of Sibiu, 550245 Sibiu, Romania.; Faculty of Medicine, Lucian Blaga University of Sibiu, 550169 Sibiu, Romania.
Jazyk:	angličtina
Zdroj:	Pathogens (Basel, Switzerland) [Pathogens] 2023 May 26; Vol. 12 (6). Date of Electronic Publication: 2023 May 26.
DOI:	10.3390/pathogens12060766
Abstrakt:	In a mutually beneficial connection with its host, the gut microbiota affects the host's nutrition, immunity, and metabolism. An increasing number of studies have shown links between certain types of disease and gut dysbiosis or specific microorganisms. Fecal microbiota transplantation (FMT) is strongly advised for the treatment of recurrent or resistant Clostridium difficile infection (CDI) due to its outstanding clinical effectiveness against CDI. The therapeutic potential of FMT for other disorders, particularly inflammatory bowel diseases and malignancies, is currently gaining more and more attention. We summarized the most recent preclinical and clinical evidence to show the promise of FMT in the management of cancer as well as complications related to cancer treatment after reviewing the most recent research on the gut microbiota and its relationship to cancer.
Databáze:	MEDLINE
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