Precision Medicine on the Effects of Microbiota on Head-Neck Diseases and Biomarkers Diagnosis.

Autor:	Inchingolo AM; Department of Interdisciplinary Medicine, University of Bari 'Aldo Moro', 70121 Bari, Italy., Malcangi G; Department of Interdisciplinary Medicine, University of Bari 'Aldo Moro', 70121 Bari, Italy., Piras F; Department of Interdisciplinary Medicine, University of Bari 'Aldo Moro', 70121 Bari, Italy., Palmieri G; Department of Interdisciplinary Medicine, University of Bari 'Aldo Moro', 70121 Bari, Italy., Settanni V; Department of Interdisciplinary Medicine, University of Bari 'Aldo Moro', 70121 Bari, Italy., Riccaldo L; Department of Interdisciplinary Medicine, University of Bari 'Aldo Moro', 70121 Bari, Italy., Morolla R; Department of Interdisciplinary Medicine, University of Bari 'Aldo Moro', 70121 Bari, Italy., Buongiorno S; Department of Interdisciplinary Medicine, University of Bari 'Aldo Moro', 70121 Bari, Italy., de Ruvo E; Department of Interdisciplinary Medicine, University of Bari 'Aldo Moro', 70121 Bari, Italy., Inchingolo AD; Department of Interdisciplinary Medicine, University of Bari 'Aldo Moro', 70121 Bari, Italy., Mancini A; Department of Interdisciplinary Medicine, University of Bari 'Aldo Moro', 70121 Bari, Italy., Inchingolo F; Department of Interdisciplinary Medicine, University of Bari 'Aldo Moro', 70121 Bari, Italy., Dipalma G; Department of Interdisciplinary Medicine, University of Bari 'Aldo Moro', 70121 Bari, Italy., Benagiano S; Department of Interdisciplinary Medicine, University of Bari 'Aldo Moro', 70121 Bari, Italy., Tartaglia GM; Department of Biomedical, Surgical and Dental Sciences, School of Dentistry, University of Milan, 20122 Milan, Italy.; UOC Maxillo-Facial Surgery and Dentistry, Fondazione IRCCS Ca Granda, Ospedale Maggiore Policlinico, 20122 Milan, Italy., Patano A; Department of Interdisciplinary Medicine, University of Bari 'Aldo Moro', 70121 Bari, Italy.
Jazyk:	angličtina
Zdroj:	Journal of personalized medicine [J Pers Med] 2023 May 31; Vol. 13 (6). Date of Electronic Publication: 2023 May 31.
DOI:	10.3390/jpm13060933
Abstrakt:	Precision medicine using highly precise technologies and big data has produced personalised medicine with rapid and reliable diagnoses and targeted therapies. The most recent studies have directed precision medicine into the study of tumours. The application of precision medicine in the oral microbiota can be used both in the field of prevention and treatment in the strictly dental field. This article aims to evaluate the interaction between microbiota and oral cancer and the presence of biomarkers as risk predictors. Materials and Methods: A literature search of PubMed, Scopus, and Web of Science was performed analysing the various interactions between microorganisms, biomarkers, and oral cancer. Results: After screening processes, 21 articles were selected for qualitative analysis. Conclusion: The correlation between oral diseases/cancers and changes in the microbiota explains the increasing utility of precision medicine in enhancing diagnosis and adapting treatment on the individual components of the microbiota. Diagnosing and treating oral diseases and cancers through precision medicine gives, as well as economic advantages to the health care system, predictable and rapid management of the patient.
Databáze:	MEDLINE
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