Ubiquinol Short-Term Supplementation Prior to Strenuous Exercise Improves Physical Performance and Diminishes Muscle Damage.

Autor: Moreno-Fernandez J; Department of Physiology, Faculty of Pharmacy, Campus Universitario de Cartuja, University of Granada, 18071 Granada, Spain.; Institute of Nutrition and Food Technology 'José Mataix Verdú', University of Granada, 18071 Granada, Spain.; Instituto de Investigación Biosanitaria (IBS), 18012 Granada, Spain., Puche-Juarez M; Department of Physiology, Faculty of Pharmacy, Campus Universitario de Cartuja, University of Granada, 18071 Granada, Spain.; Institute of Nutrition and Food Technology 'José Mataix Verdú', University of Granada, 18071 Granada, Spain.; Nutrition and Food Sciences Ph.D. Program, University of Granada, 18071 Granada, Spain., Toledano JM; Department of Physiology, Faculty of Pharmacy, Campus Universitario de Cartuja, University of Granada, 18071 Granada, Spain.; Institute of Nutrition and Food Technology 'José Mataix Verdú', University of Granada, 18071 Granada, Spain.; Nutrition and Food Sciences Ph.D. Program, University of Granada, 18071 Granada, Spain., Chirosa I; Department of Physical Education, University of Granada, 18071 Granada, Spain., Chirosa LJ; Department of Physical Education, University of Granada, 18071 Granada, Spain., Pulido-Moran M; Pharmaceutical Laboratory Farmacia Perpetuo Socorro, 18001 Granada, Spain., Kajarabille N; Department of Preventive Medicine and Public Health, University of the Basque Country (UPV/EHU), 01006 Vitoria, Spain.; Nutrition and Obesity Group, Department of Pharmacy and Food Science, Lucio Lascaray Research Institute, University of the Basque Country (UPV/EHU), 01006 Vitoria, Spain., Guisado IM; Group of Preventive Activities in the University Field of Health Sciences, Albacete Faculty of Nursing, University of Castilla-La Mancha (Universidad de Castilla-La Mancha/UCLM), 13001 Ciudad Real, Spain., Guisado R; Faculty of Health Sciences, University of Granada, 18071 Granada, Spain., Diaz-Castro J; Department of Physiology, Faculty of Pharmacy, Campus Universitario de Cartuja, University of Granada, 18071 Granada, Spain.; Institute of Nutrition and Food Technology 'José Mataix Verdú', University of Granada, 18071 Granada, Spain.; Instituto de Investigación Biosanitaria (IBS), 18012 Granada, Spain., Ochoa JJ; Department of Physiology, Faculty of Pharmacy, Campus Universitario de Cartuja, University of Granada, 18071 Granada, Spain.; Institute of Nutrition and Food Technology 'José Mataix Verdú', University of Granada, 18071 Granada, Spain.; Instituto de Investigación Biosanitaria (IBS), 18012 Granada, Spain.
Jazyk: angličtina
Zdroj: Antioxidants (Basel, Switzerland) [Antioxidants (Basel)] 2023 May 31; Vol. 12 (6). Date of Electronic Publication: 2023 May 31.
DOI: 10.3390/antiox12061193
Abstrakt: The benefits of physical exercise on health are diminished when it is non-planned, strenuous, or vigorous, which causes an increase in oxygen consumption and production of free radicals, particularly serious at the muscular level. Ubiquinol could help achieve an antioxidant, anti-inflammatory, and ergogenic effect. The aim of this study is to evaluate whether a supplementation of ubiquinol during a short period could have a positive effect on muscle aggression, physical performance, and fatigue perception in non-elite athletes after high intensity circuit weight training. One hundred healthy and well-trained men, (firemen of the Fire Department of Granada) were enrolled in a placebo-controlled, double-blinded, and randomized study, and separated into two groups: the placebo group (PG, n = 50); and the ubiquinol group (UG, n = 50), supplemented with an oral dose. Before and after the intervention, data related to the number of repetitions, muscle strength, and perceived exertion, as well as blood samples were collected. An increase was observed in the UG regarding average load and repetitions, revealing an improvement in muscle performance. Ubiquinol supplementation also reduced muscle damage markers, showing a protective effect on muscle fibers. Therefore, this study provides evidence that ubiquinol supplementation improves muscle performance and prevents muscle damage after strenuous exercise in a population of well-trained individuals who are not elite athletes.
Databáze: MEDLINE