A scoping review of current and emerging techniques for evaluation of peripheral nerve health, degeneration and regeneration: part 2, non-invasive imaging.

Autor: Mandeville R; Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA 02215, United States of America., Deshmukh S; Department of Radiology, Beth Israel Deaconess Medical Center, Boston, MA 02215, United States of America., Tan ET; Department of Radiology, Hospital for Special Surgery, New York, NY 10021, United States of America., Kumar V; Department of Radiology, Massachusetts General Hospital, Boston, MA 02114, United States of America., Sanchez B; Department Electrical and Computer Engineering, University of Utah, Salt Lake City, UT 84112, United States of America., Dowlatshahi AS; Department of Surgery, Beth Israel Deaconess Medical Center, Boston, MA 02215, United States of America., Luk J; Department of Neurosurgery, Massachusetts General Hospital, Boston, MA 02114, United States of America., See RHB; Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, United States of America., Leochico CFD; Department of Physical Medicine and Rehabilitation, St. Luke's Medical Center, Global City, Taguig, The Philippines.; Department of Rehabilitation Medicine, Philippine General Hospital, University of the Philippines Manila, Manila, The Philippines., Thum JA; Department of Neurosurgery, Massachusetts General Hospital, Boston, MA 02114, United States of America., Bazarek S; Department of Neurosurgery, Brigham and Women's Hospital, Boston, MA 02115, United States of America., Johnston B; Department of Neurosurgery, Brigham and Women's Hospital, Boston, MA 02115, United States of America., Brown J; Department of Neurosurgery, Massachusetts General Hospital, Boston, MA 02114, United States of America., Wu J; Department of Radiology, Beth Israel Deaconess Medical Center, Boston, MA 02215, United States of America., Sneag D; Department of Radiology, Hospital for Special Surgery, New York, NY 10021, United States of America., Rutkove S; Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA 02215, United States of America.
Jazyk: angličtina
Zdroj: Journal of neural engineering [J Neural Eng] 2023 Jul 24; Vol. 20 (4). Date of Electronic Publication: 2023 Jul 24.
DOI: 10.1088/1741-2552/ace217
Abstrakt: Peripheral neuroregenerative research and therapeutic options are expanding exponentially. With this expansion comes an increasing need to reliably evaluate and quantify nerve health. Valid and responsive measures of the nerve status are essential for both clinical and research purposes for diagnosis, longitudinal follow-up, and monitoring the impact of any intervention. Furthermore, novel biomarkers can elucidate regenerative mechanisms and open new avenues for research. Without such measures, clinical decision-making is impaired, and research becomes more costly, time-consuming, and sometimes infeasible. Part 1 of this two-part scoping review focused on neurophysiology. In part 2, we identify and critically examine many current and emerging non-invasive imaging techniques that have the potential to evaluate peripheral nerve health, particularly from the perspective of regenerative therapies and research.
(© 2023 IOP Publishing Ltd.)
Databáze: MEDLINE