| Autor: |
Alahmadi N; Department of Chemistry, College of Science, University of Jeddah, Jeddah 21959, Saudi Arabia., El-Said WA; Department of Chemistry, College of Science, University of Jeddah, Jeddah 21959, Saudi Arabia.; Chemistry Department, Faculty of Science, Assiut University, Assiut 71516, Egypt. |
| Jazyk: |
angličtina |
| Zdroj: |
Biosensors [Biosensors (Basel)] 2023 May 26; Vol. 13 (6). Date of Electronic Publication: 2023 May 26. |
| DOI: |
10.3390/bios13060578 |
| Abstrakt: |
The electrochemical sensing of biomarkers has attracted more and more attention due to the advantages of electrochemical biosensors, including their ease of use, excellent accuracy, and small analyte volumes. Thus, the electrochemical sensing of biomarkers has a potential application in early disease diagnosis diagnosis. Dopamine neurotransmitters have a vital role in the transmission of nerve impulses. Here, the fabrication of a polypyrrole/molybdenum dioxide nanoparticle (MoO 3 NP)-modified ITO electrode based on a hydrothermal technique followed by electrochemical polymerization is reported. Several techniques were used to investigate the developed electrode's structure, morphology, and physical characteristics, including SEM, FTIR, EDX, N 2 adsorption, and Raman spectroscopy. The results imply the formation of tiny MoO 3 NPs with an average diameter of 29.01 nm. The developed electrode was used to determine low concentrations of dopamine neurotransmitters based on cyclic voltammetry and square wave voltammetry techniques. Furthermore, the developed electrode was used for monitoring dopamine in a human serum sample. The LOD for detecting dopamine by using MoO 3 NPs/ITO electrodes based on the SWV technique was around 2.2 nmol L -1 . |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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