Caffeine Limits Expansion of Apc-Deficient Clones in the Intestine by NOTUM Inhibition.

Autor: van Driel MS; Amsterdam UMC, Location University of Amsterdam, Laboratory for Experimental Oncology and Radiobiology, Center for Experimental and Molecular Medicine, Amsterdam, The Netherlands; Cancer Center Amsterdam, Amsterdam, The Netherlands; Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, The Netherlands; Oncode Institute, Amsterdam, The Netherlands., Linssen JDG; Amsterdam UMC, Location University of Amsterdam, Laboratory for Experimental Oncology and Radiobiology, Center for Experimental and Molecular Medicine, Amsterdam, The Netherlands; Cancer Center Amsterdam, Amsterdam, The Netherlands; Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, The Netherlands; Oncode Institute, Amsterdam, The Netherlands; Amsterdam UMC, Location University of Amsterdam, Department of Gastroenterology and Hepatology, Amsterdam, The Netherlands., Flanagan DJ; Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Australia; Cancer Program, Biomedicine Discovery Institute, Monash University, Melbourne, Australia; Cancer Research UK Beatson Institute, Glasgow, United Kingdom., Vlahov N; Cancer Research UK Beatson Institute, Glasgow, United Kingdom., Nijman LE; Amsterdam UMC, Location University of Amsterdam, Laboratory for Experimental Oncology and Radiobiology, Center for Experimental and Molecular Medicine, Amsterdam, The Netherlands; Cancer Center Amsterdam, Amsterdam, The Netherlands; Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, The Netherlands; Oncode Institute, Amsterdam, The Netherlands., de Groot NE; Amsterdam UMC, Location University of Amsterdam, Laboratory for Experimental Oncology and Radiobiology, Center for Experimental and Molecular Medicine, Amsterdam, The Netherlands; Cancer Center Amsterdam, Amsterdam, The Netherlands; Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, The Netherlands; Oncode Institute, Amsterdam, The Netherlands., Elbers CC; Amsterdam UMC, Location University of Amsterdam, Laboratory for Experimental Oncology and Radiobiology, Center for Experimental and Molecular Medicine, Amsterdam, The Netherlands; Cancer Center Amsterdam, Amsterdam, The Netherlands; Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, The Netherlands; Oncode Institute, Amsterdam, The Netherlands., Koster J; Amsterdam UMC, Location University of Amsterdam, Laboratory for Experimental Oncology and Radiobiology, Center for Experimental and Molecular Medicine, Amsterdam, The Netherlands; Cancer Center Amsterdam, Amsterdam, The Netherlands., Sansom OJ; Cancer Research UK Beatson Institute, Glasgow, United Kingdom; Institute of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom., Vermeulen L; Amsterdam UMC, Location University of Amsterdam, Laboratory for Experimental Oncology and Radiobiology, Center for Experimental and Molecular Medicine, Amsterdam, The Netherlands; Cancer Center Amsterdam, Amsterdam, The Netherlands; Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, The Netherlands; Oncode Institute, Amsterdam, The Netherlands. Electronic address: l.vermeulen@amsterdamumc.nl., van Neerven SM; Amsterdam UMC, Location University of Amsterdam, Laboratory for Experimental Oncology and Radiobiology, Center for Experimental and Molecular Medicine, Amsterdam, The Netherlands; Cancer Center Amsterdam, Amsterdam, The Netherlands; Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, The Netherlands; Oncode Institute, Amsterdam, The Netherlands; Wellcome Trust-Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge, United Kingdom. Electronic address: s.m.vanneerven@amsterdamumc.nl.
Jazyk: angličtina
Zdroj: Cellular and molecular gastroenterology and hepatology [Cell Mol Gastroenterol Hepatol] 2023; Vol. 16 (4), pp. 652-655. Date of Electronic Publication: 2023 Jun 24.
DOI: 10.1016/j.jcmgh.2023.06.008
Databáze: MEDLINE