The analysis between clinicopathological aspect of early-onset vs. late-onset colorectal cancer and mortality rate: a cross-sectional study.
| Autor: | Lukman K; Departments of Surgery., Mulyawan A; Departments of Surgery., Nugrahani AD; Obstetrics and Gynaecology., Rudiman R; Departments of Surgery., Primastari E; Anatomical Pathology, Faculty of Medicine, Universitas Padjadjaran, Dr. Hasan Sadikin General Hospital, Bandung, West Java, Indonesia. |
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| Jazyk: | angličtina |
| Zdroj: | Annals of medicine and surgery (2012) [Ann Med Surg (Lond)] 2023 May 03; Vol. 85 (6), pp. 2496-2501. Date of Electronic Publication: 2023 May 03 (Print Publication: 2023). |
| DOI: | 10.1097/MS9.0000000000000757 |
| Abstrakt: | Early-onset colorectal cancer (CRC) has different clinical and pathological characteristics compared with late-onset CRC. Mortality rate as a postoperative outcome is a patient's postoperative outcome considered based on the state of life or death. The objective of this research is to analyse the comparison between clinicopathological aspect of early-onset vs. late-onset CRC as well as their correlation with the mortality rate in Indonesia to support global data. Material and Methods: The authors performed a case-control study on 170 subjects with CRC from November 2021 to November 2022 in a Tertiary Hospital in Bandung. Data were extracted from electronic medical records CRC Registry. Bivariate and correlation analyses were used to analyse the difference between variables using IBM SPSS 24.0. P less than 0.05 was considered statistically significant. Results: Anaemia and tumour location variables were significantly different in the early-onset group compared with the late-onset group ( P <0.001). It was also found that anaemia ( P <0.001), pathological features ( P <0.001), and tumour location ( P =0.013) had significantly low correlation with onset of CRC (r=0.325; r=0.397; r=0.342, respectively). Conclusion: There is no statistically significant correlation between the clinicopathological features of CRC in both onset and mortality rates in this study. Competing Interests: The authors declare that we have no conflicts of interest. (Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc.) |
| Databáze: | MEDLINE |
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