Automated cell count in body fluids: a review.

Autor:	Alcaide Martín MJ; Committee of Laboratory Tests, Spanish Society of Laboratory Medicine (SEQC-ML), Barcelona, Spain.; Hematologic Biology Committee, Spanish Society of Laboratory Medicine (SEQC-ML), Barcelona, Spain., Altimira Queral L; Committee of Laboratory Tests, Spanish Society of Laboratory Medicine (SEQC-ML), Barcelona, Spain., Sahuquillo Frías L; Committee of Laboratory Tests, Spanish Society of Laboratory Medicine (SEQC-ML), Barcelona, Spain., Valiña Amado L; Committee of Laboratory Tests, Spanish Society of Laboratory Medicine (SEQC-ML), Barcelona, Spain., Merino A; Hematologic Biology Committee, Spanish Society of Laboratory Medicine (SEQC-ML), Barcelona, Spain., García de Guadiana-Romualdo L; Committee of Laboratory Tests, Spanish Society of Laboratory Medicine (SEQC-ML), Barcelona, Spain.
Jazyk:	English; Spanish; Castilian
Zdroj:	Advances in laboratory medicine [Adv Lab Med] 2021 Mar 15; Vol. 2 (2), pp. 149-177. Date of Electronic Publication: 2021 Mar 15 (Print Publication: 2021).
DOI:	10.1515/almed-2021-0011
Abstrakt:	Body fluid cell counting provides valuable information for the diagnosis and treatment of a variety of conditions. Chamber cell count and cellularity analysis by optical microscopy are considered the gold-standard method for cell counting. However, this method has a long turnaround time and limited reproducibility, and requires highly-trained personnel. In the recent decades, specific modes have been developed for the analysis of body fluids. These modes, which perform automated cell counting, are incorporated into hemocytometers and urine analyzers. These innovations have been rapidly incorporated into routine laboratory practice. At present, a variety of analyzers are available that enable automated cell counting for body fluids. Nevertheless, these analyzers have some limitations and can only be operated by highly-qualified laboratory professionals. In this review, we provide an overview of the most relevant automated cell counters currently available for body fluids, the interpretation of the parameters measured by these analyzers, their main analytical features, and the role of optical microscopy as automated cell counters gain ground. Competing Interests: Conflict of interest: The authors report no conflicts of interest. (© 2021 María José Alcaide Martín et al., published by De Gruyter, Berlin/Boston.)
Databáze:	MEDLINE
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