Methicillin-resistant and methicillin-sensitive Staphylococcus aureus in pork industry workers, Catalonia, Spain.

Autor:	Quero S; Infectious Diseases Unit, Health Sciences Research Institute of the Germans Trias i Pujol Foundation, Badalona, Barcelona, Spain.; CIBER de Enfermedades Respiratorias, Madrid, Spain., Serras-Pujol M; Internal Medicine Department, Hospital Universitari de Vic, Barcelona, Spain.; Department of Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain., Párraga-Niño N; Infectious Diseases Unit, Health Sciences Research Institute of the Germans Trias i Pujol Foundation, Badalona, Barcelona, Spain., Torres C; Area de Bioquímica y Biología Molecular, Universidad de La Rioja, Logroño, Spain., Navarro M; Microbiology Department, Hospital Universitari de Vic, Barcelona, Spain., Vilamala A; Microbiology Department, Hospital Universitari de Vic, Barcelona, Spain., Puigoriol E; Epidemiology Department, Hospital Universitari de Vic, Barcelona, Spain., de Los Ríos JD; Internal Medicine Department, Hospital Universitari de Vic, Barcelona, Spain., Arqué E; Infectious Diseases Unit, Health Sciences Research Institute of the Germans Trias i Pujol Foundation, Badalona, Barcelona, Spain., Serra-Pladevall J; Microbiology Department, Hospital Universitari de Vic, Barcelona, Spain., Romero A; Fundació Lluita Contra les Infeccions, Infectious Diseases Department, Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona, Spain., Molina D; Fundació Lluita Contra les Infeccions, Infectious Diseases Department, Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona, Spain., Paredes R; Fundació Lluita Contra les Infeccions, Infectious Diseases Department, Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona, Spain.; IrsiCaixa AIDS Reseach institute, Hospital Germans Trias i Pujol, Badalona, Barcelona, Spain.; CIBERINFECT, ISCIII, Madrid, Spain., Pedro-Botet ML; Infectious Diseases Unit, Health Sciences Research Institute of the Germans Trias i Pujol Foundation, Badalona, Barcelona, Spain.; CIBER de Enfermedades Respiratorias, Madrid, Spain.; Department of Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain.; Fundació Lluita Contra les Infeccions, Infectious Diseases Department, Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona, Spain., Reynaga E; Infectious Diseases Unit, Health Sciences Research Institute of the Germans Trias i Pujol Foundation, Badalona, Barcelona, Spain.; Internal Medicine Department, Hospital Universitari de Vic, Barcelona, Spain.; Department of Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain.; Fundació Lluita Contra les Infeccions, Infectious Diseases Department, Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona, Spain.
Jazyk:	angličtina
Zdroj:	One health (Amsterdam, Netherlands) [One Health] 2023 Apr 07; Vol. 16, pp. 100538. Date of Electronic Publication: 2023 Apr 07 (Print Publication: 2023).
DOI:	10.1016/j.onehlt.2023.100538
Abstrakt:	Background: Methicillin-resistant S. aureus (MRSA) especially ST398, is a zoonotic agent. This study aimed to determine the prevalence of methicillin-susceptible S. aureus (MSSA) and MRSA among workers in the pork production chain. Methods: 659 workers associated with 123 pig farms, livestock transporters, one pig slaughterhouse, pork transporters and 23 pork butcheries were studied for S. aureus recovery, and all isolates were characterized (antibiotic resistance, MLST and spa -typing). Results: The prevalence of S. aureus was 35.5%, 75.6% of isolates being MRSA. The prevalence of MRSA was 68.7% (149/217) among pig farm, 33.9% (19/56) livestock transporters, 2.9% (9/306) slaughterhouse, 0% in pork transporters (0/36) and butchery workers (0/44). Of the 234  S. aureus -positive workers, 100% (149/149) of pig farm workers, 82.6% (19/23) of livestock transporters, and 16.4% (9/55) of slaughterhouse workers carried MRSA isolates ( p  < 0.001). Of the workers who had contact with live swine, 61.8% (178/288) were S. aureus -positive, MRSA being detected in 96.1% of cases (p < 0.001). The most frequent lineage among MRSA were: ST398 (97.7%; 173/177) and ST1 (1.7%; 3/177); and among MSSA were ST30 (19.2%; 11/57) and ST5 (10.5%; 6/57). The most frequent spa -types among MRSA were t011 (93.8%, 166/177) and t1451 (2.25%, 4/177), and among MSSA: t084 (10.5%, 6/57) and t021 (7.0%, 4/57). All MRSA isolates showed resistance to tetracycline, 92.7% to clindamycin, 81.9% to erythromycin and 40.1% to cotrimoxazole. Conclusions: Pig industry workers having occupational contact with live animals present a high risk of colonization of MRSA, especially by MRSA-ST398. Prevention measures should be intensified in any employment sector involving live animals. Competing Interests: RP participated in advisory activities related to COVID-19 and HIV for Gilead, ViiV Healthcare, GSK, MSD, Theratechnologies, Lilly and Roche, and received research funds awarded to his institution from Gilead, ViiV healthcare and MSD. All other authors declare no competing interests. (© 2023 The Authors.)
Databáze:	MEDLINE
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