The role of neuronal plasticity in cervical spondylotic myelopathy surgery: functional assessment and prognostic implication.

Autor: Bonosi L; Neurosurgical Clinic, AOUP 'Paolo Giaccone', Post Graduate Residency Program in NeurologiSurgery, Department of Biomedicine Neurosciences and Advanced Diagnostics, School of Medicine, University of Palermo, 90127, Palermo, Italy. lapo.bonosi@gmail.com., Musso S; Neurosurgical Clinic, AOUP 'Paolo Giaccone', Post Graduate Residency Program in NeurologiSurgery, Department of Biomedicine Neurosciences and Advanced Diagnostics, School of Medicine, University of Palermo, 90127, Palermo, Italy., Cusimano LM; Neurosurgical Clinic, AOUP 'Paolo Giaccone', Post Graduate Residency Program in NeurologiSurgery, Department of Biomedicine Neurosciences and Advanced Diagnostics, School of Medicine, University of Palermo, 90127, Palermo, Italy., Porzio M; Neurosurgical Clinic, AOUP 'Paolo Giaccone', Post Graduate Residency Program in NeurologiSurgery, Department of Biomedicine Neurosciences and Advanced Diagnostics, School of Medicine, University of Palermo, 90127, Palermo, Italy., Giovannini EA; Neurosurgical Clinic, AOUP 'Paolo Giaccone', Post Graduate Residency Program in NeurologiSurgery, Department of Biomedicine Neurosciences and Advanced Diagnostics, School of Medicine, University of Palermo, 90127, Palermo, Italy., Benigno UE; Neurosurgical Clinic, AOUP 'Paolo Giaccone', Post Graduate Residency Program in NeurologiSurgery, Department of Biomedicine Neurosciences and Advanced Diagnostics, School of Medicine, University of Palermo, 90127, Palermo, Italy., Giammalva GR; Neurosurgical Clinic, AOUP 'Paolo Giaccone', Post Graduate Residency Program in NeurologiSurgery, Department of Biomedicine Neurosciences and Advanced Diagnostics, School of Medicine, University of Palermo, 90127, Palermo, Italy., Gerardi RM; Neurosurgical Clinic, AOUP 'Paolo Giaccone', Post Graduate Residency Program in NeurologiSurgery, Department of Biomedicine Neurosciences and Advanced Diagnostics, School of Medicine, University of Palermo, 90127, Palermo, Italy., Brunasso L; Neurosurgical Clinic, AOUP 'Paolo Giaccone', Post Graduate Residency Program in NeurologiSurgery, Department of Biomedicine Neurosciences and Advanced Diagnostics, School of Medicine, University of Palermo, 90127, Palermo, Italy., Costanzo R; Neurosurgical Clinic, AOUP 'Paolo Giaccone', Post Graduate Residency Program in NeurologiSurgery, Department of Biomedicine Neurosciences and Advanced Diagnostics, School of Medicine, University of Palermo, 90127, Palermo, Italy., Paolini F; Neurosurgical Clinic, AOUP 'Paolo Giaccone', Post Graduate Residency Program in NeurologiSurgery, Department of Biomedicine Neurosciences and Advanced Diagnostics, School of Medicine, University of Palermo, 90127, Palermo, Italy., Sciortino A; Neurosurgical Clinic, AOUP 'Paolo Giaccone', Post Graduate Residency Program in NeurologiSurgery, Department of Biomedicine Neurosciences and Advanced Diagnostics, School of Medicine, University of Palermo, 90127, Palermo, Italy., Campisi BM; Neurosurgical Clinic, AOUP 'Paolo Giaccone', Post Graduate Residency Program in NeurologiSurgery, Department of Biomedicine Neurosciences and Advanced Diagnostics, School of Medicine, University of Palermo, 90127, Palermo, Italy., Giardina K; Neurosurgical Clinic, AOUP 'Paolo Giaccone', Post Graduate Residency Program in NeurologiSurgery, Department of Biomedicine Neurosciences and Advanced Diagnostics, School of Medicine, University of Palermo, 90127, Palermo, Italy., Scalia G; Department of Neurosurgery, ARNAS Garibaldi, P.O. Garibaldi Nesima, 95122, Catania, Italy., Iacopino DG; Neurosurgical Clinic, AOUP 'Paolo Giaccone', Post Graduate Residency Program in NeurologiSurgery, Department of Biomedicine Neurosciences and Advanced Diagnostics, School of Medicine, University of Palermo, 90127, Palermo, Italy., Maugeri R; Neurosurgical Clinic, AOUP 'Paolo Giaccone', Post Graduate Residency Program in NeurologiSurgery, Department of Biomedicine Neurosciences and Advanced Diagnostics, School of Medicine, University of Palermo, 90127, Palermo, Italy.
Jazyk: angličtina
Zdroj: Neurosurgical review [Neurosurg Rev] 2023 Jun 26; Vol. 46 (1), pp. 149. Date of Electronic Publication: 2023 Jun 26.
DOI: 10.1007/s10143-023-02062-9
Abstrakt: Cervical spondylotic myelopathy (CSM) is a degenerative disease representing the most common spinal cord disorder in the adult population. It is characterized by chronic compression leading to neurological dysfunction due to static and dynamic injury of the spinal cord in cervical spine. These insidious damage mechanisms can result in the reorganization of cortical and subcortical areas. The cerebral cortex can reorganize due to spinal cord injury and may play a role in preserving neurological function. To date, the gold standard treatment of cervical myelopathy is surgery, comprising anterior, posterior, and combined approaches. However, the complex physiologic recovery processes involving cortical and subcortical neural reorganization following surgery are still inadequately understood. It has been demonstrated that diffusion MRI and functional imaging and techniques, such as transcranial magnetic stimulation (TMS) or functional magnetic resonance imaging (fMRI), can provide new insights into the diagnosis and prognosis of CSM. This review aims to shed light on the state-of-the-art regarding the pattern of cortical and subcortical areas reorganization and recovery before and after surgery in CSM patients, underlighting the critical role of neuroplasticity.
(© 2023. The Author(s).)
Databáze: MEDLINE
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