An unusual case of Takayasu arteritis presenting as isolated severe aortic regurgitation: A case report.

Autor: Simkhada A; Department of Pathology, Institute of Medicine, Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Bagmati Province, Nepal., Acharya P; Department of Pathology, Institute of Medicine, Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Bagmati Province, Nepal. Electronic address: prithaacharya121@gmail.com., Tiwari SB; Department of Pathology, Madan Bhandari Academy of Health Sciences, Hetauda, Bagmati Province, Nepal., K C B; Department of Pathology, Institute of Medicine, Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Bagmati Province, Nepal.
Jazyk: angličtina
Zdroj: International journal of surgery case reports [Int J Surg Case Rep] 2023 Jul; Vol. 108, pp. 108407. Date of Electronic Publication: 2023 Jun 15.
DOI: 10.1016/j.ijscr.2023.108407
Abstrakt: Introduction: Takayasu arteritis is a chronic granulomatous vasculitis involving the large vessels, mainly the aorta and its branches.
Case Presentation: We report a case of a young female who presented with severe shortness of breath and easy fatigability. Examination revealed a diastolic murmur and imaging studies revealed a severe aortic regurgitation with aneurysm of the aortic root and ascending aorta.
Clinical Discussion: Modified Bentall's procedure was performed and sample sent for histopathology which showed granulomatous inflammation of the aorta with elastic fibre destruction in the medial layer. Infective causes of aortic aneurysm were ruled out and a diagnosis of Takayasu arteritis was made on the basis of clinical, radiological and histological findings.
Conclusion: This case highlights the unusual presentation of Takayasu arteritis in which the patient had severe aortic regurgitation and aneurysm of the ascending aorta without steno-occlusive lesion elsewhere.
Competing Interests: Conflict of interest statement There are no conflicts of interest in the creation of this case report as declared by the authors.
(Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved.)
Databáze: MEDLINE