History of high household pesticide use and Parkinson's disease in Brazil.

Autor: Moura DD; Universidade Federal do Pará, Instituto de Ciências Médicas, Belém, PA, Brazil. Electronic address: daf.dalledone@gmail.com., Borges V; Universidade Federal de São Paulo, Departamento de Neurologia, São Paulo, SP, Brazil. Electronic address: vanderci.borges@gmail.com., Ferraz HB; Departamento de Farmacologia, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil. Electronic address: henrique_ferraz@uol.com.br., Schuh AFS; Departamento de Farmacologia, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil; Serviço de Neurologia, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil. Electronic address: schuh.afs@gmail.com., de Mello Rieder CR; Departamento de Neurologia, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, RS, Brazil. Electronic address: carlosrieder@gmail.com., Mata IF; Lerner Research Institute, Genomic Medicine, Cleveland Clinic, Cleveland, OH, USA. Electronic address: matai@ccf.org., Brito MMCM; Universidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Departamento de Neurociências e Ciências Comportamentais, Ribeirão Preto, SP, Brazil. Electronic address: manuelinamacruz@gmail.com., Tumas V; Universidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Departamento de Neurociências e Ciências Comportamentais, Ribeirão Preto, SP, Brazil. Electronic address: tumasv@fmrp.usp.br., Santos-Lobato BL; Universidade Federal do Pará, Instituto de Ciências Médicas, Belém, PA, Brazil; Serviço de Neurologia, Hospital Ophir Loyola, Belém, PA, Brazil. Electronic address: bruls4@ufpa.br.
Jazyk: angličtina
Zdroj: Parkinsonism & related disorders [Parkinsonism Relat Disord] 2023 Aug; Vol. 113, pp. 105493. Date of Electronic Publication: 2023 Jun 19.
DOI: 10.1016/j.parkreldis.2023.105493
Abstrakt: The prevalence of Parkinson's disease (PD) is growing worldwide and household pesticides exposure may be related to this phenomenon. We showed that individuals with high exposure to household pesticides have two times more risk of developing PD. Household pesticide exposure did not impact age at PD onset.
Competing Interests: Declaration of competing interest No COI.
(Copyright © 2023. Published by Elsevier Ltd.)
Databáze: MEDLINE