Anopheles vector distribution and malaria transmission dynamics in Gbêkê region, central Côte d'Ivoire.

Autor: Koffi AA; Institut Pierre Richet (IPR)/Institut National de Santé Publique (INSP), Bouaké, Côte d'Ivoire.; Vector Control Product Evaluation Centre (VCPEC), Institut Pierre Richet (VCPEC-IPR)/INSP, Bouaké, Côte d'Ivoire., Camara S; Institut Pierre Richet (IPR)/Institut National de Santé Publique (INSP), Bouaké, Côte d'Ivoire. soromanec@gmail.com.; Vector Control Product Evaluation Centre (VCPEC), Institut Pierre Richet (VCPEC-IPR)/INSP, Bouaké, Côte d'Ivoire. soromanec@gmail.com., Ahoua Alou LP; Institut Pierre Richet (IPR)/Institut National de Santé Publique (INSP), Bouaké, Côte d'Ivoire.; Vector Control Product Evaluation Centre (VCPEC), Institut Pierre Richet (VCPEC-IPR)/INSP, Bouaké, Côte d'Ivoire., Oumbouke WA; Vector Control Product Evaluation Centre (VCPEC), Institut Pierre Richet (VCPEC-IPR)/INSP, Bouaké, Côte d'Ivoire.; Innovative Vector Control Consortium, IVCC, Liverpool, UK., Wolie RZ; Vector Control Product Evaluation Centre (VCPEC), Institut Pierre Richet (VCPEC-IPR)/INSP, Bouaké, Côte d'Ivoire.; Unité de Recherche et de Pédagogie de Génétique, Université Félix Houphouët-Boigny, UFR Biosciences, Abidjan, Côte d'Ivoire., Tia IZ; Vector Control Product Evaluation Centre (VCPEC), Institut Pierre Richet (VCPEC-IPR)/INSP, Bouaké, Côte d'Ivoire.; Centre d'Entomologie Médicale et Vétérinaire, Université Allassane Ouattara, Bouaké, Côte d'Ivoire., Sternberg ED; Tropical Health LLP, London, UK., Yapo FHA; Vector Control Product Evaluation Centre (VCPEC), Institut Pierre Richet (VCPEC-IPR)/INSP, Bouaké, Côte d'Ivoire., Koffi FM; Vector Control Product Evaluation Centre (VCPEC), Institut Pierre Richet (VCPEC-IPR)/INSP, Bouaké, Côte d'Ivoire., Assi SB; Institut Pierre Richet (IPR)/Institut National de Santé Publique (INSP), Bouaké, Côte d'Ivoire., Cook J; MRC International Statistics and Epidemiology Group, London School of Hygiene and Tropical Medicine, London, UK., Thomas MB; Department of Entomology & Nematology, The University of Florida, Gainesville, FL, USA., N'Guessan R; Institut Pierre Richet (IPR)/Institut National de Santé Publique (INSP), Bouaké, Côte d'Ivoire.; Vector Control Product Evaluation Centre (VCPEC), Institut Pierre Richet (VCPEC-IPR)/INSP, Bouaké, Côte d'Ivoire.; Department of Disease Control, London School of Hygiene and Tropical Medicine, London, UK.
Jazyk: angličtina
Zdroj: Malaria journal [Malar J] 2023 Jun 22; Vol. 22 (1), pp. 192. Date of Electronic Publication: 2023 Jun 22.
DOI: 10.1186/s12936-023-04623-1
Abstrakt: Background: A better understanding of vector distribution and malaria transmission dynamics at a local scale is essential for implementing and evaluating effectiveness of vector control strategies. Through the data gathered in the framework of a cluster randomized controlled trial (CRT) evaluating the In2Care (Wageningen, Netherlands) Eave Tubes strategy, the distribution of the Anopheles vector, their biting behaviour and malaria transmission dynamics were investigated in Gbêkê region, central Côte d'Ivoire.
Methods: From May 2017 to April 2019, adult mosquitoes were collected monthly using human landing catches (HLC) in twenty villages in Gbêkê region. Mosquito species wereidentified morphologically. Monthly entomological inoculation rates (EIR) were estimated by combining the HLC data with mosquito sporozoite infection rates measured in a subset of Anopheles vectors using PCR. Finally, biting rate and EIR fluctuations were fit to local rainfall data to investigate the seasonal determinants of mosquito abundance and malaria transmission in this region.
Results: Overall, Anopheles gambiae, Anopheles funestus, and Anopheles nili were the three vector complexes found infected in the Gbêkê region, but there was a variation in Anopheles vector composition between villages. Anopheles gambiae was the predominant malaria vector responsible for 84.8% of Plasmodium parasite transmission in the area. An unprotected individual living in Gbêkê region received an average of 260 [222-298], 43.5 [35.8-51.29] and 3.02 [1.96-4] infected bites per year from An. gambiae, An. funestus and An. nili, respectively. Vector abundance and malaria transmission dynamics varied significantly between seasons and the highest biting rate and EIRs occurred in the months of heavy rainfall. However, mosquitoes infected with malaria parasites remained present in the dry season, despite the low density of mosquito populations.
Conclusion: These results demonstrate that the intensity of malaria transmission is extremely high in Gbêkê region, especially during the rainy season. The study highlights the risk factors of transmission that could negatively impact current interventions that target indoor control, as well as the urgent need for additional vector control tools to target the population of malaria vectors in Gbêkê region and reduce the burden of the disease.
(© 2023. The Author(s).)
Databáze: MEDLINE
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