Esophageal Neuroendocrine Carcinoma Presenting After Definitive Chemoradiation of Squamous Cell Carcinoma in the Same Location.

Autor:	Prenatt Z; Department of Internal Medicine, St. Luke's University Health Network, Bethlehem, PA., Liaquat H; Department of Gastroenterology, St. Luke's University Health Network, Bethlehem, PA., Shupp B; Department of Internal Medicine, St. Luke's University Health Network, Bethlehem, PA., Stoll L; Department of Pathology, St. Luke's University Health Network, Bethlehem, PA., Schneider Y; Department of Gastroenterology, St. Luke's University Health Network, Bethlehem, PA.
Jazyk:	angličtina
Zdroj:	ACG case reports journal [ACG Case Rep J] 2023 Jun 19; Vol. 10 (6), pp. e01091. Date of Electronic Publication: 2023 Jun 19 (Print Publication: 2023).
DOI:	10.14309/crj.0000000000001091
Abstrakt:	Esophageal neuroendocrine carcinoma is very rare and highly aggressive. An 85-year-old man with a history of esophageal squamous cell carcinoma in remission presented 4 years after definitive chemoradiation with new-onset dysphagia. Endoscopy with biopsy revealed high-grade malignancy consistent with neuroendocrine carcinoma. Treatment options were limited to chemotherapy because of his metastatic disease, and he unfortunately died 14 months after diagnosis. The occurrence of esophageal neuroendocrine carcinoma in a site of prior squamous cell carcinoma is very uncommon, and this likely represents a case of radiation-induced malignancy. Therefore, when undergoing radiotherapy, patients and providers should discuss the possibility of this life-threatening complication. (© 2023 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu