The anterior olfactory nucleus revisited - An emerging role for neuropathological conditions?

Autor: Brunert D; Institute of Physiology, Medical Faculty, Otto-von-Guericke-University, 39120 Magdeburg, Germany; Institute for Physiology and Cell Biology, University of Veterinary Medicine Hannover, Foundation, 30173 Hanover, Germany., Medinaceli Quintela R; Institute for Physiology and Cell Biology, University of Veterinary Medicine Hannover, Foundation, 30173 Hanover, Germany., Rothermel M; Institute of Physiology, Medical Faculty, Otto-von-Guericke-University, 39120 Magdeburg, Germany. Electronic address: markus.rothermel@med.ovgu.de.
Jazyk: angličtina
Zdroj: Progress in neurobiology [Prog Neurobiol] 2023 Sep; Vol. 228, pp. 102486. Date of Electronic Publication: 2023 Jun 19.
DOI: 10.1016/j.pneurobio.2023.102486
Abstrakt: Olfaction is an important sensory modality for many species and greatly influences animal and human behavior. Still, much about olfactory perception remains unknown. The anterior olfactory nucleus is one of the brain's central early olfactory processing areas. Located directly posterior to the olfactory bulb in the olfactory peduncle with extensive in- and output connections and unique cellular composition, it connects olfactory processing centers of the left and right hemispheres. Almost 20 years have passed since the last comprehensive review on the anterior olfactory nucleus has been published and significant advances regarding its anatomy, function, and pathophysiology have been made in the meantime. Here we briefly summarize previous knowledge on the anterior olfactory nucleus, give detailed insights into the progress that has been made in recent years, and map out its emerging importance in translational research of neurological diseases.
Competing Interests: Declaration of Competing Interest None.
(Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved.)
Databáze: MEDLINE
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