Correlates of serum estradiol concentration among postmenopausal women in Ilorin, North-Central Nigeria.

Autor:	Odeigah LO; From the Family Medicine Department, University of Ilorin Teaching Hospital., Obalowu IA; Family Medicine Department, General Hospital Ilorin, Ilorin, Kwara State, Nigeria., Alabi AN; From the Family Medicine Department, University of Ilorin Teaching Hospital., Mohammed A; Family Medicine Department, General Hospital Ilorin, Ilorin, Kwara State, Nigeria., Ademola CO; Family Medicine Department, General Hospital Ilorin, Ilorin, Kwara State, Nigeria., Oyeleke OA; Family Medicine Department, General Hospital Ilorin, Ilorin, Kwara State, Nigeria.
Jazyk:	angličtina
Zdroj:	Menopause (New York, N.Y.) [Menopause] 2023 Aug 01; Vol. 30 (8), pp. 849-854. Date of Electronic Publication: 2023 Jun 20.
DOI:	10.1097/GME.0000000000002207
Abstrakt:	Objectives: There are limited data on the associated factors of circulating endogenous estradiol among Nigerian postmenopausal women. The main objective of this study is to assess the relationship between serum estradiol levels and some menstrual, clinical, and sociodemographic factors in postmenopausal women attending a family medicine clinic in Nigeria. Methods: This was a hospital-based cross-sectional study involving 372 postmenopausal women. Sociodemographic, menstrual, and clinical data of the participants were collected, and their serum estradiol concentrations were assayed. The collected data were analyzed using IBM SPSS version 21 statistical software. A χ2 test of association and logistic regression analysis were done to identify significant correlates of serum estradiol concentration among the participants. Results: The mean ages at menarche and menopause among the participants were 15.6 and 48.1 years respectively. Approximately half of them (51.1%) were receiving chronic medical care for systemic hypertension and/or diabetes. The mean estradiol concentration of the participants in the study was 20.69 pg/mL. The participants' marital status and clinical presentation pattern (chronic vs others) were found to have statistically significant associations with their serum estradiol concentration; P = 0.048 and P = 0.001, respectively. Logistic regression analysis revealed that only the clinical presentation pattern had a significant relationship with serum estradiol concentration among the participants ( P = 0.002). Conclusion: Of all the studied factors, the only significant correlate of low serum estradiol concentration found in this study was chronic medical care presentation for hypertension and/or diabetes. Competing Interests: Financial disclosure/conflicts of interest: None reported. (Copyright © 2023 by The North American Menopause Society.)
Databáze:	MEDLINE
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