Base-mediated cascade synthesis of indole diolefins: a route to spiro[cyclopentene-indole]thiones and thiepino[2,3- b ]indoles.
| Autor: | Muthusamy S; School of Chemistry, Bharathidasan University, Tiruchirappalli-620024, India. muthu@bdu.ac.in., Naveen R; School of Chemistry, Bharathidasan University, Tiruchirappalli-620024, India. muthu@bdu.ac.in., Kumar MDS; School of Chemistry, Bharathidasan University, Tiruchirappalli-620024, India. muthu@bdu.ac.in. |
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| Jazyk: | angličtina |
| Zdroj: | Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2023 Jul 06; Vol. 59 (55), pp. 8560-8563. Date of Electronic Publication: 2023 Jul 06. |
| DOI: | 10.1039/d3cc01870a |
| Abstrakt: | Base-mediated cascade reactions of 3-hydroxymethyl-3-propenylindole-2-thiones afforded diolefins and involved deformylation, thioenolate alkylation and the thio-Claisen rearrangement. Subsequent ring-closing metathesis reactions of the diolefins furnished 3-spiro[cyclopentene-indole]-2-thiones or thiepino[2,3- b ]indoles. |
| Databáze: | MEDLINE |
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