A personalized intervention to prevent depression in primary care based on risk predictive algorithms and decision support systems: protocol of the e-predictD study.

Autor:	Bellón JA; Biomedical Research Institute of Malaga (IBIMA Plataforma Bionand), Málaga, Spain.; Prevention and Health Promotion Research Network (redIAPP), ISCIII, Madrid, Spain.; Network for Research on Chronicity, Primary Care, and Prevention and Health Promotion (RICAPPS), ISCIII, Madrid, Spain.; 'El Palo' Health Centre, Servicio Andaluz de Salud (SAS), Málaga, Spain.; Department of Public Health and Psychiatry, University of Málaga (UMA), Málaga, Spain., Rodríguez-Morejón A; Biomedical Research Institute of Malaga (IBIMA Plataforma Bionand), Málaga, Spain.; Prevention and Health Promotion Research Network (redIAPP), ISCIII, Madrid, Spain.; Network for Research on Chronicity, Primary Care, and Prevention and Health Promotion (RICAPPS), ISCIII, Madrid, Spain.; Department of Personality, Evaluation and Psychological Treatment, University of Málaga (UMA), Málaga, Spain., Conejo-Cerón S; Biomedical Research Institute of Malaga (IBIMA Plataforma Bionand), Málaga, Spain.; Prevention and Health Promotion Research Network (redIAPP), ISCIII, Madrid, Spain.; Network for Research on Chronicity, Primary Care, and Prevention and Health Promotion (RICAPPS), ISCIII, Madrid, Spain., Campos-Paíno H; Biomedical Research Institute of Malaga (IBIMA Plataforma Bionand), Málaga, Spain.; Prevention and Health Promotion Research Network (redIAPP), ISCIII, Madrid, Spain.; Network for Research on Chronicity, Primary Care, and Prevention and Health Promotion (RICAPPS), ISCIII, Madrid, Spain., Rodríguez-Bayón A; Prevention and Health Promotion Research Network (redIAPP), ISCIII, Madrid, Spain.; Network for Research on Chronicity, Primary Care, and Prevention and Health Promotion (RICAPPS), ISCIII, Madrid, Spain.; Centro de Salud San José, Distrito Sanitario Jaén Norte, Servicio Andaluz de Salud (SAS), Linares, Jaén, Spain., Ballesta-Rodríguez MI; Prevention and Health Promotion Research Network (redIAPP), ISCIII, Madrid, Spain.; Network for Research on Chronicity, Primary Care, and Prevention and Health Promotion (RICAPPS), ISCIII, Madrid, Spain.; Centro de Salud Federico del Castillo, Distrito Sanitario Jaén, Servicio Andaluz de Salud (SAS), Jaén, Spain., Rodríguez-Sánchez E; Prevention and Health Promotion Research Network (redIAPP), ISCIII, Madrid, Spain.; Network for Research on Chronicity, Primary Care, and Prevention and Health Promotion (RICAPPS), ISCIII, Madrid, Spain.; Unidad de Investigación de Atención Primaria de Salamanca (APISAL), Gerencia de Atención Primaria de Salamanca, Instituto de Investigación Biomédica de Salamanca (IBSAL), Salamanca, Spain.; Department of Medicine, University of Salamanca (USAL), Salamanca, Spain., Mendive JM; Prevention and Health Promotion Research Network (redIAPP), ISCIII, Madrid, Spain.; Network for Research on Chronicity, Primary Care, and Prevention and Health Promotion (RICAPPS), ISCIII, Madrid, Spain.; 'La Mina' Health Centre, Institut Català de la Salut (ICS), Barcelona, Spain., López Del Hoyo Y; Prevention and Health Promotion Research Network (redIAPP), ISCIII, Madrid, Spain.; Network for Research on Chronicity, Primary Care, and Prevention and Health Promotion (RICAPPS), ISCIII, Madrid, Spain.; Instituto de Investigación Sanitaria de Aragón (IISA), Universidad de Zaragoza (UNIZAR), Zaragoza, Spain., Luna JD; Prevention and Health Promotion Research Network (redIAPP), ISCIII, Madrid, Spain.; Network for Research on Chronicity, Primary Care, and Prevention and Health Promotion (RICAPPS), ISCIII, Madrid, Spain.; Department of Statistics and Operational Research, University of Granada (UGR), Granada, Spain., Tamayo-Morales O; Prevention and Health Promotion Research Network (redIAPP), ISCIII, Madrid, Spain.; Network for Research on Chronicity, Primary Care, and Prevention and Health Promotion (RICAPPS), ISCIII, Madrid, Spain.; Unidad de Investigación de Atención Primaria de Salamanca (APISAL), Gerencia de Atención Primaria de Salamanca, Instituto de Investigación Biomédica de Salamanca (IBSAL), Salamanca, Spain., Moreno-Peral P; Biomedical Research Institute of Malaga (IBIMA Plataforma Bionand), Málaga, Spain.; Prevention and Health Promotion Research Network (redIAPP), ISCIII, Madrid, Spain.; Network for Research on Chronicity, Primary Care, and Prevention and Health Promotion (RICAPPS), ISCIII, Madrid, Spain.; Department of Personality, Evaluation and Psychological Treatment, University of Málaga (UMA), Málaga, Spain.
Jazyk:	angličtina
Zdroj:	Frontiers in psychiatry [Front Psychiatry] 2023 Jun 02; Vol. 14, pp. 1163800. Date of Electronic Publication: 2023 Jun 02 (Print Publication: 2023).
DOI:	10.3389/fpsyt.2023.1163800
Abstrakt:	The predictD is an intervention implemented by general practitioners (GPs) to prevent depression, which reduced the incidence of depression-anxiety and was cost-effective. The e-predictD study aims to design, develop, and evaluate an evolved predictD intervention to prevent the onset of major depression in primary care based on Information and Communication Technologies, predictive risk algorithms, decision support systems (DSSs), and personalized prevention plans (PPPs). A multicenter cluster randomized trial with GPs randomly assigned to the e-predictD intervention + care-as-usual (CAU) group or the active-control + CAU group and 1-year follow-up is being conducted. The required sample size is 720 non-depressed patients (aged 18-55 years), with moderate-to-high depression risk, under the care of 72 GPs in six Spanish cities. The GPs assigned to the e-predictD-intervention group receive brief training, and those assigned to the control group do not. Recruited patients of the GPs allocated to the e-predictD group download the e-predictD app, which incorporates validated risk algorithms to predict depression, monitoring systems, and DSSs. Integrating all inputs, the DSS automatically proposes to the patients a PPP for depression based on eight intervention modules: physical exercise, social relationships, improving sleep, problem-solving, communication skills, decision-making, assertiveness, and working with thoughts. This PPP is discussed in a 15-min semi-structured GP-patient interview. Patients then choose one or more of the intervention modules proposed by the DSS to be self-implemented over the next 3 months. This process will be reformulated at 3, 6, and 9 months but without the GP-patient interview. Recruited patients of the GPs allocated to the control-group+CAU download another version of the e-predictD app, but the only intervention that they receive via the app is weekly brief psychoeducational messages (active-control group). The primary outcome is the cumulative incidence of major depression measured by the Composite International Diagnostic Interview at 6 and 12 months. Other outcomes include depressive symptoms (PHQ-9) and anxiety symptoms (GAD-7), depression risk (predictD risk algorithm), mental and physical quality of life (SF-12), and acceptability and satisfaction ('e-Health Impact' questionnaire) with the intervention. Patients are evaluated at baseline and 3, 6, 9, and 12 months. An economic evaluation will also be performed (cost-effectiveness and cost-utility analysis) from two perspectives, societal and health systems. Trial Registration: ClinicalTrials.gov, identifier: NCT03990792. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2023 Bellón, Rodríguez-Morejón, Conejo-Cerón, Campos-Paíno, Rodríguez-Bayón, Ballesta-Rodríguez, Rodríguez-Sánchez, Mendive, López del Hoyo, Luna, Tamayo-Morales and Moreno-Peral.)
Databáze:	MEDLINE
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